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Table 1 Cox proportional hazards models for relapse-free survival using the NKI 295 patient test data set – model containing the clinical variables and the VEGF profile

From: A compact VEGF signature associated with distant metastases and poor outcomes

Variable DF Estimate Standard Error Chi-Square Pr > ChiSq Hazard Ratio 95% Hazard Ratio Confidence Limits
Age 1 -0.05508 0.01622 11.5365 0.0007 0.946 0.917 0.977
ER 1 -0.12785 0.23563 0.2944 0.5874 0.88 0.555 1.397
Grade2vs1 1 0.8058 0.31181 6.6784 0.0098 2.238 1.215 4.124
Grade3vs1 1 0.76706 0.32265 5.6519 0.0174 2.153 1.144 4.053
Tsize 1 0.37409 0.19444 3.7017 0.0544 1.454 0.993 2.128
node 1 0.33066 0.17801 3.4504 0.0632 1.392 0.982 1.973
Treatment 1 -0.65688 0.27811 5.5788 0.0182 0.518 0.301 0.894
VEGF_3group 1 0.47238 0.14838 10.1355 0.0015 1.604 1.199 2.145