Table 4 Cox proportional hazards models for relapse-free survival using the NKI 295 patient test data set – model containing the clinical variables and the VEGF-profile as a continuous variable
From: A compact VEGF signature associated with distant metastases and poor outcomes
Variable | DF | Estimate | Standard Error | Chi-Square | Pr > ChiSq | Hazard Ratio | 95% Hazard Ratio Confidence Limits | |
|---|---|---|---|---|---|---|---|---|
Age | 1 | -0.0589 | 0.01639 | 12.906 | 0.0003 | 0.943 | 0.913 | 0.974 |
ER | 1 | 0.00607 | 0.25196 | 0.0006 | 0.9808 | 1.006 | 0.614 | 1.649 |
Grade2vs1 | 1 | 0.82592 | 0.31135 | 7.0367 | 0.008 | 2.284 | 1.241 | 4.204 |
Grade3vs1 | 1 | 0.78226 | 0.32128 | 5.9284 | 0.0149 | 2.186 | 1.165 | 4.104 |
Tsize | 1 | 0.31513 | 0.19566 | 2.5941 | 0.1073 | 1.37 | 0.934 | 2.011 |
node | 1 | 0.3314 | 0.17655 | 3.5233 | 0.0605 | 1.393 | 0.985 | 1.969 |
Treatment | 1 | -0.61996 | 0.27417 | 5.1133 | 0.0237 | 0.538 | 0.314 | 0.921 |
VEGF_Continuous | 1 | 0.43301 | 0.12298 | 12.3972 | 0.0004 | 1.542 | 1.212 | 1.962 |