Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection

Table 6 ¹H nuclear magnetic resonance (NMR) data of colorectal cancer (CRC) biomarker pool (sample A) and their methyl esters

Types of protons	CRC biomarker pool	Methyl esters of CRC biomarker pool
CH ₃	0.83-0.90	0.83-0.90
CH ₂	1.21-1.24, m	1.21-1.24, m
-CH ₂CH₂COOH	1.57-1.65, m	1.53-1.69, m
-CH ₂CH=CH-	1.98-2.08, m	1.94-2.03, m
CH ₂COO	2.23-2.28, m	2.23-2.31, m
-CH=CH-CH ₂-CH=	2.75-2.79, m	2.74-2.82, m
OCH ₃	-	3.64, s
-CH(OH)CH=	3.45-3.71, 4.03-4.26	4.02-4.12, 4.16-4.26, 4.58-4.60
-CH=	5.10-5.47, m	5.08-5.40, m
-CH(OH)CH=	5.76-5.91, m	5.75-5.90, m

*NMR solvent is CDCl₃, signals assigned using 2D NMR experiments (HMQC and HMBC)

ISSN: 1741-7015