Skip to main content


Table 2 Proteins found unique to the African-American dataset that are reported to be involved in breast cancer, as annotated by Ingenuity Systems or BIOBASE.

From: The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo

Symbol Entrez gene name Location Entrez gene ID
ADAM12 ADAM metallopeptidase domain 12 Plasma membrane 8038
ADRA2C Adrene gic, alpha-2C-, receptor Plasma membrane 152
AKR1C1 Aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1) Cytoplasm 1645
ANK1 Ankyrin 1, erythrocytic Plasma membrane 286
ANXA1 Annexin A1 Plasma membrane 301
ANXA5 Annexin A5 Plasma membrane 308
BCAS1 Breast carcinoma amplified sequence 1 Unknown 8537
CAMKK1 Calcium/calmodulin-dependent protein kinase kinase 1, alpha Cytoplasm 84254
CANX Calnexin Cytoplasm 821
CASP1 Caspase 1, apoptosis-related cysteine peptidase (interleukin 1, convertase Cytoplasm 834
CD69 CD69 molecule Plasma membrane 969
CDH11 Cadherin 11, type 2, OB-cadherin (osteoblast) Plasma membrane 1009
CDR2 Cerebellar degeneration-related protein 2, 62 kDa Cytoplasm 1039
CTSD Cathepsin D Cytoplasm 1509
DAB2 Disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) Plasma membrane 1601
DECR1 2,4-Dienoyl CoA reductase 1, mitochondrial Cytoplasm 1666
DFNA5 Deafness, autosomal dominant 5 Unknown 1687
DLC1 Deleted in liver cancer 1 Cytoplasm 10395
EDNRB Endothelin receptor type B Plasma membrane 1910
EEF1A1 Eukaryotic translation elongation factor 1 alpha 1 Cytoplasm 1915
ERBB4 V-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) Plasma membrane 2066
FBLN1 Fibulin 1 Extracellular space 2192
GAPDH Glyceraldehyde-3-phosphate dehydrogenase Cytoplasm 2597
GRIN2D Glutamate receptor, ionotropic, N-methyl d-aspartate 2D Plasma membrane 2906
GSN Gelsolin (amyloidosis, Finnish type) Extracellular space 2934
HSPB1 Heat shock 27 kDa protein 1 Cytoplasm 3315
IGF1R Insulin-like growth factor 1 receptor Plasma membrane 3480
KDR Kinase insert domain receptor (a type III receptor tyrosine kinase) Plasma membrane 3791
LTF Lactotransferrin Extracellular space 4057
MET Met proto-oncogene (hepatocyte growth factor receptor) Plasma membrane 4233
MMP14 Matrix metallopeptidase 14 (membrane-inserted) Extracellular space 4323
MUC6 Mucin 6, oligomeric mucus/gel-forming Extracellular space 4588
NLRP1 NLR family, pyrin domain containing 1 Cytoplasm 22861
ORM1 Orosomucoid 1 Extracellular space 5004
PDGFRB Platelet-derived growth factor receptor, beta polypeptide Plasma membrane 5159
PLXNA1 Plexin A1 Plasma membrane 5361
POR P450 (cytochrome) oxidoreductase Cytoplasm 5447
PTPRG Protein tyrosine phosphatase, receptor type, G Plasma membrane 5793
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 Cytoplasm 6093
S100A9 S100 calcium binding protein A9 Cytoplasm 6280
SERPINA3 Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase), member 3 Extracellular space 12
SERPINB5 Serpin peptidase inhibitor, clade B (ovalbumin), member 5 Extracellular space 5268
SOD1 Superoxide dismutase 1, soluble Cytoplasm 6647
SOD2 Superoxide dismutase 2, mitochondrial Cytoplasm 6648
SYK Spleen tyrosine kinase Cytoplasm 6850
TAGLN Transgelin Cytoplasm 6876
TJP1 Tight junction protein 1 (zona occludens 1) Plasma membrane 7082
TXNRD1 Thioredoxin reductase 1 Cytoplasm 7296