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Table 1 Included randomized controlled trials.

From: Triple antiplatelet therapy for preventing vascular events: a systematic review and meta-analysis

     Control group      
Study N Age Male (%) Asp TP GP Triple group Heparin Length of treatment Length of follow-up (months) Quality*
NSTE-ACS            
ADVANCE[41] 202 69 68   Tirofiban 48 h 6 A
ELISA-2[42] 328 64 71   Tirofiban - 12 h 1 A
ISAR-REACT-2[43] 2,022 66 75   Abciximab 12 h 1 A
PROTECT-TIMI-30[44] 857 60 67   Eptifibatide 24 h 48 h A
STEMI            
ADMIRAL[45] 300 61 82   Abciximab 12 h 6 A
ACE[46] 400 64 77   Abciximab 12 h 6 A
CADILLAC [47] 2082 60 73   Abciximab 12 h 6 B
Ernst/1[48] 60 61 74   Abciximab 12 h 1 B
Ernst/2[48] 60 60 82   Tirofiban 12 h 1 B
Ernst/3[48] 59 61 76   Tirofiban high dose 12 h 1 B
ISAR 2[30] 401 61 76   Abciximab 12 h 1 B
Neumann[31] 200 60 77   Abciximab 12 h 1 B
Petronio[49] 31 57 87   Abciximab 12 h 1 B
Kim[50] 60 63 70   Cilostazol 1 month 1 B
Elective PCI            
Claeys[51] 200 67 70   Abciximab 12 h 6 B
EPISTENT[52] 1,603 59 75   Abciximab 13 h 1 A
ESPRIT[35] 2,064 62 73   Eptifibatide 24 h 1 B
ISAR-REACT[53] 2,159 66 77   Abciximab 12 h 1 A
ISAR-SMART-2[54] 502 66 73   Abciximab 12 h 12 A
ISAR-SWEET[55] 701 68 75   Abciximab 12 h 12 A
TOPSTAR[56] 96 65 75   tirofiban 42 h 9 A
MR PCI/1[57] 60 61 85 - Clopidogrel 30 days 1 A
MR PCI/2[57] 60 56 85 - Clopidogrel 30 days 1 A
DECLARE-Long[58] 500 61 64   Cilostazol - 6 months 6 A
DECLARE-DIABETES[59] 400 61 58   Cilostazol - 6 months 6 A
Min[60] 59 62 66   Cilostazol 1 month 6 A
CREST[61] 705 60 74   Cilostazol - 6 months 6 A
Han[62] 1212 60 73   Cilostazol - 6 months 12 A
  1. *Quality scale: A, true randomization and allocation concealed; B, process of randomization not given and concealment of allocation unclear.
  2. Asp, aspirin; GP, glycoprotein IIb/IIIa receptor antagonists (abciximab, tirofiban, eptifibatide); MI, myocardial infarction; NSTEACS, non-ST elevation acute coronary syndrome; PCI, percutaneous coronary interventions; TP, thienopyridine (clopidogrel, ticlopidine).