|
Study name
|
Study characteristics
|
Quality assessment
|
|---|
| |
Tx
|
Country
|
Diag
|
Outcome
|
No. sessions
|
Type of data
|
FU (weeks)
|
Total N
|
Rand.
|
AC
|
ITT
|
% attrition (Intv)
|
% attrition (Ctl)
|
|---|
|
Barrett 2001 [67]
|
PST
|
USA
|
Dep - minor or dys
|
HDRS < 7
|
6
|
D
|
11
|
161
|
WC
|
WC
|
Y
|
18
|
16
|
|
Boot 1994 [58]
|
COU
|
UK
|
Mixed Anx and Dep
|
GHQ
|
6
|
C
|
6
|
192
|
AA
|
U
|
N
|
46
|
40
|
|
Brodaty 1983 [66]
|
PP
|
AUS
|
Mixed Anx and Dep
|
GHQ
|
8
|
C
|
8
|
78
|
AA
|
U
|
N
|
65
|
26
|
|
Catalan 1991 [68]
|
PST
|
UK
|
Mixed Anx and Dep
|
PSE
|
4
|
C
|
11
|
47
|
AA
|
U
|
N
|
0
|
0
|
|
Dowrick 2000 [69]
|
PST
|
EU
|
Dep - MDD or dys
|
BDI
|
6
|
C
|
26
|
317
|
AA
|
WC
|
Y
|
23
|
26
|
|
Earll 1982 [46]
|
CBT
|
UK
|
Mixed Anx and Dep
|
DSSI/sAD *
|
7.7
|
D
|
32
|
50
|
AA
|
U
|
N
|
16**
|
|
Friedli 1997 [59]
|
COU
|
UK
|
Mixed Anx and Dep
|
BDI
|
9
|
C
|
12
|
136
|
AA
|
AA
|
Y
|
16
|
23
|
|
Harvey 1998 [60]
|
COU
|
UK
|
Mixed Anx and Dep
|
HADS
|
6
|
C
|
16
|
162
|
AA
|
U
|
Y
|
31
|
25
|
|
Hemmings 1997 [61]
|
COU
|
UK
|
Mixed Anx and Dep
|
MHSI
|
5.7
|
C
|
16
|
188
|
AA
|
U
|
N
|
16
|
23
|
|
Holden 1989 [62]
|
COU
|
UK
|
Dep - MDD
|
RDC
|
8
|
D
|
12
|
50
|
AA
|
U
|
N
|
0
|
0
|
|
Kendrick 2005 [70]
|
PST
|
UK
|
Mixed Anx and Dep
|
CIS-R
|
6
|
C
|
26
|
168
|
WC
|
WC
|
Y
|
20 †
|
31†
|
|
Lang 2006 [71]
|
PST
|
USA
|
Mixed Anx and Dep
|
BSI-D
|
4
|
C
|
12
|
62
|
AA
|
U
|
Y
|
34
|
17
|
|
Lindsay 1987 [47]
|
CBT
|
UK
|
Anx - GAD
|
GHQ-28
|
8
|
C
|
4
|
20
|
AA
|
U
|
N
|
0
|
0
|
|
Liu 2007 [72]
|
PST
|
TA
|
Mixed Anx and Dep
|
CIS-R
|
2.27
|
C
|
16
|
169
|
WC
|
AA
|
Y
|
25
|
22
|
|
Lynch 1997 [73]
|
PST
|
USA
|
Dep - minor
|
HDRS
|
6
|
C
|
7
|
29
|
AA
|
U
|
N
|
27
|
7
|
|
Lynch 2004 [74]
|
PST
|
USA
|
Dep - minor
|
HDRS
|
6
|
C
|
6
|
36
|
AA
|
U
|
N
|
50
|
28
|
|
Marks 1985 [48]
|
CBT
|
UK
|
Anx - phobic
|
PS
|
6
|
C
|
26
|
92
|
AA
|
U
|
N
|
37
|
20
|
|
Mynors-Wallis 1995 [75]
|
PST
|
UK
|
Dep - MDD
|
HDRS
|
6
|
C
|
12
|
55
|
AA
|
U
|
Y
|
0
|
0
|
|
Mynors-Wallis 1997 [76]
|
PST
|
UK
|
Mixed Anx and Dep
|
CIS
|
4.5
|
C
|
26
|
70
|
AA
|
AA
|
N
|
20
|
13
|
|
Power 1989 [49]
|
CBT
|
UK
|
Anx - GAD
|
HAM-A
|
4
|
C
|
6
|
21
|
AA
|
U
|
Y
|
0
|
0
|
|
Power 1990 [51]
|
CBT
|
UK
|
Anx - GAD
|
CGI = 1
|
7
|
D
|
10
|
79
|
AA
|
U
|
N
|
0
|
0
|
|
Power 2000 [50]
|
CBT
|
UK
|
Anx - panic
|
HAM-A
|
6
|
C
|
12
|
72
|
AA
|
U
|
N
|
16
|
17
|
|
Prendegast 2001 [52]
|
CBT
|
AUS
|
Dep - mixed
|
EPDS < 10
|
6
|
D
|
26
|
37
|
AA
|
U
|
N
|
0
|
0
|
|
Robson 1984 [53]
|
CBT
|
UK
|
Mixed Anx and Dep
|
PS
|
3.7
|
C
|
14
|
429
|
AA
|
U
|
N
|
0 ††
|
0 ††
|
|
Schreuders 2007 [77]
|
PST
|
NL
|
Mixed Anx and Dep
|
HADS
|
6
|
C
|
12
|
175
|
AA
|
WC
|
N
|
30
|
22
|
|
Scott 1992 [54]
|
CBT
|
UK
|
Dep - MDD
|
HDRS
|
9.8
|
C
|
16
|
60
|
AA
|
AA
|
Y
|
3
|
3
|
|
Scott 1997 [55]
|
CBT
|
UK
|
Dep - MDD
|
HDRS
|
6
|
C
|
7
|
48
|
AA
|
U
|
N
|
25
|
33
|
|
Sharp 1996 [56]
|
CBT
|
UK
|
Anx - panic
|
HAM-A ‡
|
7
|
D
|
13
|
154
|
AA
|
U
|
Y
|
21§
|
24§
|
|
Sharp 2004 [57]
|
CBT
|
UK
|
Anx - panic
|
HAM-A
|
8
|
C
|
12
|
59
|
AA
|
U
|
Y
|
16
|
14
|
|
Simpson 2003 [63]
|
COU
|
UK
|
Dep - mixed
|
BDI
|
5
|
C
|
26
|
145
|
AA
|
U
|
Y
|
11
|
10
|
|
Van Schaik 2006 [65]
|
IPT
|
NL
|
Dep - MDD
|
MADRS
|
8
|
C
|
26
|
143
|
WC
|
WC
|
Y
|
16
|
16
|
|
Ward 2000 [27]
|
CBT
|
UK
|
Dep - mixed
|
BDI
|
5
|
C
|
16
|
197
|
AA
|
U
|
Y
|
11
|
8
|
| |
COU
| | | |
6.4
| | | | | | |
8
| |
|
Wickberg 1996 [64]
|
COU
|
SW
|
Dep - mixed
|
MADRS ¶
|
6
|
D
|
7
|
45
|
AA
|
U
|
N
|
0
|
0
|
|
Williams 2000 [78]
|
PST
|
USA
|
Dep - minor or dys
|
HDRS < 7
|
6
|
D
|
11
|
278
|
WC
|
AA
|
Y
|
18§
|
15§
|
- * Patients were categorized as not 'personally ill' by study authors.
- ** Number randomized to each group not reported by study authors.
-
† We used missing data that were imputed from a regression analysis that took account of the baseline information for each participant with missing data rather than from last observation carried forward because of differential attrition between study groups.
-
†† Attrition not reported by study authors; therefore we assumed there was no missing data.
-
‡ Study authors defined response as a clinically significant change.
-
§ For the purposes of the meta-analysis, participants with missing data were assumed to have had a poor outcome.
-
¶ Study authors defined response as a substantial improvement.
- AA, adequately addressed; AC, allocation concealment; AUS, Australia; Anx, anxiety; BDI, Beck Depression Inventory; BSI-D, Brief Symptom Inventory - Depression scale; C, continuous; CBT, cognitive behavioural therapy; CES-D, Center for Epidemiologic Studies Depression Scale; CGI, Clinical Global Impression; CIS-R, Clinical Interview Schedule - Revised; COU, Counselling; Ctl, control; D, dichotomous; Dep, depression; Dep - mixed, mixed depressive diagnoses including minor depression; Diag, diagnosis; DSSI/sAD, Delusions-Symptoms-States Inventory/states of Anxiety and Depression; dys, dysthymia; EPDS, Edinburgh Postnatal Depression Scale; EU, European countries; GHQ, General Health Questionnaire; HADS, Hospital Anxiety and Depression Scale; HAM-A, Hamilton Anxiety Rating Scale; HDRS, Hamilton Depression Rating Scale; Intv, intervention; IPT, Interpersonal psychotherapy; ITT, intention-to-treat analysis; MADRS, Montgomery-Åsberg Depression Rating Scale; MDD, major depressive disorder; MHSI, Mental Health Symptom index;; Mixed Anx and Dep, mixed anxiety and depression diagnoses; N, number randomized; NL, Netherlands; PP, Psychodynamic psychotherapy; PS, psychiatric symptoms; PSE, Present State Examination; PST, problem solving therapy; Rand., randomization; RDC, Research Diagnostic Criteria; SW, Sweden; TA, Taiwan; Tx, treatment; U, unclear; WC, well covered; Y, yes.
