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Table 1 Details of included studies

From: Brief psychological therapies for anxiety and depression in primary care: meta-analysis and meta-regression

Study name Study characteristics Quality assessment
  Tx Country Diag Outcome No. sessions Type of data FU (weeks) Total N Rand. AC ITT % attrition (Intv) % attrition (Ctl)
Barrett 2001 [67] PST USA Dep - minor or dys HDRS < 7 6 D 11 161 WC WC Y 18 16
Boot 1994 [58] COU UK Mixed Anx and Dep GHQ 6 C 6 192 AA U N 46 40
Brodaty 1983 [66] PP AUS Mixed Anx and Dep GHQ 8 C 8 78 AA U N 65 26
Catalan 1991 [68] PST UK Mixed Anx and Dep PSE 4 C 11 47 AA U N 0 0
Dowrick 2000 [69] PST EU Dep - MDD or dys BDI 6 C 26 317 AA WC Y 23 26
Earll 1982 [46] CBT UK Mixed Anx and Dep DSSI/sAD * 7.7 D 32 50 AA U N 16**
Friedli 1997 [59] COU UK Mixed Anx and Dep BDI 9 C 12 136 AA AA Y 16 23
Harvey 1998 [60] COU UK Mixed Anx and Dep HADS 6 C 16 162 AA U Y 31 25
Hemmings 1997 [61] COU UK Mixed Anx and Dep MHSI 5.7 C 16 188 AA U N 16 23
Holden 1989 [62] COU UK Dep - MDD RDC 8 D 12 50 AA U N 0 0
Kendrick 2005 [70] PST UK Mixed Anx and Dep CIS-R 6 C 26 168 WC WC Y 20 † 31†
Lang 2006 [71] PST USA Mixed Anx and Dep BSI-D 4 C 12 62 AA U Y 34 17
Lindsay 1987 [47] CBT UK Anx - GAD GHQ-28 8 C 4 20 AA U N 0 0
Liu 2007 [72] PST TA Mixed Anx and Dep CIS-R 2.27 C 16 169 WC AA Y 25 22
Lynch 1997 [73] PST USA Dep - minor HDRS 6 C 7 29 AA U N 27 7
Lynch 2004 [74] PST USA Dep - minor HDRS 6 C 6 36 AA U N 50 28
Marks 1985 [48] CBT UK Anx - phobic PS 6 C 26 92 AA U N 37 20
Mynors-Wallis 1995 [75] PST UK Dep - MDD HDRS 6 C 12 55 AA U Y 0 0
Mynors-Wallis 1997 [76] PST UK Mixed Anx and Dep CIS 4.5 C 26 70 AA AA N 20 13
Power 1989 [49] CBT UK Anx - GAD HAM-A 4 C 6 21 AA U Y 0 0
Power 1990 [51] CBT UK Anx - GAD CGI = 1 7 D 10 79 AA U N 0 0
Power 2000 [50] CBT UK Anx - panic HAM-A 6 C 12 72 AA U N 16 17
Prendegast 2001 [52] CBT AUS Dep - mixed EPDS < 10 6 D 26 37 AA U N 0 0
Robson 1984 [53] CBT UK Mixed Anx and Dep PS 3.7 C 14 429 AA U N 0 †† 0 ††
Schreuders 2007 [77] PST NL Mixed Anx and Dep HADS 6 C 12 175 AA WC N 30 22
Scott 1992 [54] CBT UK Dep - MDD HDRS 9.8 C 16 60 AA AA Y 3 3
Scott 1997 [55] CBT UK Dep - MDD HDRS 6 C 7 48 AA U N 25 33
Sharp 1996 [56] CBT UK Anx - panic HAM-A ‡ 7 D 13 154 AA U Y 21§ 24§
Sharp 2004 [57] CBT UK Anx - panic HAM-A 8 C 12 59 AA U Y 16 14
Simpson 2003 [63] COU UK Dep - mixed BDI 5 C 26 145 AA U Y 11 10
Van Schaik 2006 [65] IPT NL Dep - MDD MADRS 8 C 26 143 WC WC Y 16 16
Ward 2000 [27] CBT UK Dep - mixed BDI 5 C 16 197 AA U Y 11 8
  COU     6.4        8  
Wickberg 1996 [64] COU SW Dep - mixed MADRS ¶ 6 D 7 45 AA U N 0 0
Williams 2000 [78] PST USA Dep - minor or dys HDRS < 7 6 D 11 278 WC AA Y 18§ 15§
  1. * Patients were categorized as not 'personally ill' by study authors.
  2. ** Number randomized to each group not reported by study authors.
  3. We used missing data that were imputed from a regression analysis that took account of the baseline information for each participant with missing data rather than from last observation carried forward because of differential attrition between study groups.
  4. †† Attrition not reported by study authors; therefore we assumed there was no missing data.
  5. Study authors defined response as a clinically significant change.
  6. § For the purposes of the meta-analysis, participants with missing data were assumed to have had a poor outcome.
  7. Study authors defined response as a substantial improvement.
  8. AA, adequately addressed; AC, allocation concealment; AUS, Australia; Anx, anxiety; BDI, Beck Depression Inventory; BSI-D, Brief Symptom Inventory - Depression scale; C, continuous; CBT, cognitive behavioural therapy; CES-D, Center for Epidemiologic Studies Depression Scale; CGI, Clinical Global Impression; CIS-R, Clinical Interview Schedule - Revised; COU, Counselling; Ctl, control; D, dichotomous; Dep, depression; Dep - mixed, mixed depressive diagnoses including minor depression; Diag, diagnosis; DSSI/sAD, Delusions-Symptoms-States Inventory/states of Anxiety and Depression; dys, dysthymia; EPDS, Edinburgh Postnatal Depression Scale; EU, European countries; GHQ, General Health Questionnaire; HADS, Hospital Anxiety and Depression Scale; HAM-A, Hamilton Anxiety Rating Scale; HDRS, Hamilton Depression Rating Scale; Intv, intervention; IPT, Interpersonal psychotherapy; ITT, intention-to-treat analysis; MADRS, Montgomery-Åsberg Depression Rating Scale; MDD, major depressive disorder; MHSI, Mental Health Symptom index;; Mixed Anx and Dep, mixed anxiety and depression diagnoses; N, number randomized; NL, Netherlands; PP, Psychodynamic psychotherapy; PS, psychiatric symptoms; PSE, Present State Examination; PST, problem solving therapy; Rand., randomization; RDC, Research Diagnostic Criteria; SW, Sweden; TA, Taiwan; Tx, treatment; U, unclear; WC, well covered; Y, yes.