Table 3 Overall effect of cryotherapy on human papillomavirus (HPV) acquisition/reactivation and stratified analyses among HIV-negative women

Crude hazard ratio (HR)*

0.45 (0.28 to 0.71)

Stratified analyses

Age:

   35-39

0.42 (0.20 to 0.91)

   40-49

0.38 (0.19 to 0.73)

   50-65

0.98 (0.29 to 3.28)

Marital status:

   Married

0.55 (0.29 to 1.04)

   Not married

0.35 (0.18 to 0.69)

Lifetime sexual partners:

   ≥ 5

0.31 (0.11 to 0.86)

   < 5

0.50 (0.30 to 0.83)

Sexual activities

At baseline (1 month prior to baseline):

   Not active

0.44 (0.17 to 1.15)

   Sexually active

0.45 (0.27 to 0.76)

In first month (1 month after baseline):

   Not sexually active

0.38 (0.19 to 0.78)

   Sexually active

0.48 (0.26 to 0.88)