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Table 3 Overall effect of cryotherapy on human papillomavirus (HPV) acquisition/reactivation and stratified analyses among HIV-negative women

From: Reduced acquisition and reactivation of human papillomavirus infections among older women treated with cryotherapy: results from a randomized trial in South Africa

  Hazard ratio (95% CI) (N = 540)
Crude hazard ratio (HR)* 0.45 (0.28 to 0.71)
Stratified analyses  
Age:  
   35-39 0.42 (0.20 to 0.91)
   40-49 0.38 (0.19 to 0.73)
   50-65 0.98 (0.29 to 3.28)
Marital status:  
   Married 0.55 (0.29 to 1.04)
   Not married 0.35 (0.18 to 0.69)
Lifetime sexual partners:  
   ≥ 5 0.31 (0.11 to 0.86)
   < 5 0.50 (0.30 to 0.83)
Sexual activities  
At baseline (1 month prior to baseline):  
   Not active 0.44 (0.17 to 1.15)
   Sexually active 0.45 (0.27 to 0.76)
In first month (1 month after baseline):  
   Not sexually active 0.38 (0.19 to 0.78)
   Sexually active 0.48 (0.26 to 0.88)
  1. *The adjusted HR = 0.49 (0.29 to 0.81), adjusted for age, age at first sex, lifetime sex partners, sex and condom use at months 1 and 6.