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Table 3 Recommended procedure for substitution of vitamins during total parenteral nutrition (personal communication Ramsauer and Vetter, Berlin, Germany).

From: Managing hyperemesis gravidarum: a multimodal challenge

Parenteral nutrition via peripheral venous access
Main infusion Adjuvants (daily dose) Speed of operation
500 mL glucose-infusion 5% • 200 mg vitamin B1 (thiaminchloride), • 200 mg vitamin B6 (pyridoxine), • 200 μg vitamin B12 (cyanocobalamine), • 2000 mg vitamin C (ascorbic acid) 50 mL/h
Parenteral nutrition via central venous access
Main infusion Adjuvants (daily dose) Speed of operation
500 mL glucose-infusion 40% • 200 mg vitamin B1(thiaminchloride), • 200 mg vitamin B6 (pyridoxine), • 200 μg vitamin B12 (cyanocobalamine), • 2000 mg vitamin C (ascorbic acid) 50 mL/h