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Table 1 Structure of families included in the study.

From: An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study

No. of affecteds No. of unaffecteds No. of families with
   CAD CAD before 50 years* MI †
1 1 164 149 122
1 2 439 235 362
1 >2 49 38 39
2 1 158 46 78
2 2 42 15 23
2 >2 18 6 14
≥ 3 ≥1 21 4 11
Total families   891 493 660
Total affecteds   1154 568 802
Total unaffecteds   1545 855 1204
  1. * In this setting, individuals affected after 50 years were considered as unphenotyped
  2. † For this trait coding, individuals free of myocardial infarction (MI) but affected by other forms of coronary artery disease (CAD) were considered unphenotyped.
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