Table 5 Joint effects of the IL1-CCC haplotype and other risk factors on CAD.

CAD

IL1 CCC

0.047

1.22

1.00

1.47

Sex (baseline = female)

<0.001

4.86

4.00

5.91

Ever smoked

<0.001

2.01

1.62

2.50

Hypertension

<0.001

3.16

2.55

3.92

Overall test (4df)

P < 0.0001

CAD before 50 years

IL1 CCC

0.002

1.53

1.17

2.01

Sex (baseline = female)

<0.001

6.44

4.78

8.67

Ever smoked

<0.001

3.03

2.16

4.26

Hypertension

<0.001

3.57

2.56

5.00

Overall test (4df)

P < 0.0001