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Table 5 Joint effects of the IL1-CCC haplotype and other risk factors on CAD.

From: An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study

Trait Factor P_value Odds ratio 95 CI*  
CAD IL1 CCC 0.047 1.22 1.00 1.47
  Sex (baseline = female) <0.001 4.86 4.00 5.91
  Ever smoked <0.001 2.01 1.62 2.50
  Hypertension <0.001 3.16 2.55 3.92
  Overall test (4df) P < 0.0001    
CAD before 50 years IL1 CCC 0.002 1.53 1.17 2.01
  Sex (baseline = female) <0.001 6.44 4.78 8.67
  Ever smoked <0.001 3.03 2.16 4.26
  Hypertension <0.001 3.57 2.56 5.00
  Overall test (4df) P < 0.0001    
  1. * 95% confidence interval (CI)
  2. CAD, coronary artery disease.
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