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Table 7 Regulation of stress relevant gene sets comparing the intervention groups to the controls with regard to changes in gene expression (FDR ≤ 5%)

From: Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers

   Number of Upregulated Gene Sets
   Antioxidant-Rich Diet Group Kiwifruit Group
GSEA Gene Set Collections 1 Number of Gene Sets in Collection 2 Up Down Up Down
DNA and repair 61 15 0 13 0
Hypoxia* 33 4 0 1 0
Apoptosis 206 11 0 4 0
Cytokine* 164 1 0 0 0
Interleukin* 98 1 0 1 0
Immune* and response 62 1 0 1 1
Inflammation 7 1 0 0 0
Stress 91 6 0 0 0
Stress and response 51 4 0 0 0
Oxidative and stress 32 2 0 0 0
C3TFT3 582 13 4 3 0
  1. 1Collections of gene sets were obtained using a gene set browser from the Broad Institute web site http://www.broad.mit.edu/gsea/ defined by the listed keywords. For some keywords we used truncated search terms as indicated by *.
  2. 2Number of gene sets passing the gene set size filter.
  3. 3The C3 TFT gene set collection consists of gene sets grouped by common transcription factor binding sites.