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Table 3 Included studies design, participants and attrition

From: The effects of increased dose of exercise-based therapies to enhance motor recovery after stroke: a systematic review and meta-analysis

Study Design Participants Attrition
(cumulative)
   Number & gender Mean (SD)
age (years)
Stroke lesioned hemisphere Stroke classification Mean (SD) time
after stroke (days)
  
   Control Extra Control Extra Control Extra Control Extra Control Extra Control Extra
Cooke 2009 Multi-centre
Observer- blind
RCT
38 (21 M) 35 (22 M) 66.4 (13.7) 67.5 (11.3) 17 right 13 right All anterior circulation stroke 36.8 (22.5) 32.4 (21.3) 7 by 6 weeks
21 by 6 weeks
3 by 6 weeks
10 by 12 weeks
Donaldson 2009 Single centre
Observer- blind
RCT
10 (5 M) 10 (5 M) 72.7 (14.5) 73.0 (8.6) 5 right 4 right All anterior circulation stroke 13.4 (4.4) 25.6 (15.5) 2 by 6 weeks
7 by 12 weeks
0 by 6 weeks
4 by 12 weeks
GAPS 2004 Multi-centre
Observer- blind
RCT
35 (17 M) 35 (24 M) 67 (10) 68 (11) 15 right 15 right TACI = 7
PACI = 18
LACI = 8
POCI = 1
unsure = 1
TACI = 6
PACI = 15
LACI = 10
POCI = 2
unsure = 2
25 days
(range 6-71)
0 by 4 weeks
1 by 3 months
1 by 6 months
1 by 4 weeks
3 by 3 months
4 by 6 months
Lincoln 1999 Single centre
Observer- blind
RCT
95 (45 M) 94 (51 M) Median 73
(IQR 64-80)
Median 73
(IQR 65-81)
38 right 47 right TACI = 7
PACI = 29
LACI = 13
POCI = 0
unsure = 46
TACI = 9
PACI = 31
LACI = 11
POCI = 0
unsure = 43
1-5 weeks after stroke 5 by 5 weeks
11 by 3 months
14 by 6 months
7 by 5 weeks
10 by 3 months
13 by 6 months
Kwakkel 1999 & 2002 Multi-centre
Observer- blind
RCT
37 (14 M) Arm group
33 (16 M)
64.1 (15) Arm group
69 (9.8)
24 right Arm group
19 right
TACI = 25
PACI = 9
LACI = 3
POCI = 0
unsure = 0
Arm group
TACI = 19
PACI = 11
LACI = 3
POCI = 0
unsure = 0
7.5 (2.9) Arm group
7.2 (2.8)
3 by 20 weeks
3 by 26 weeks
4 by 52 weeks
Arm group
4 by 20 weeks
4 by 26 weeks
5 by 52 weeks
   Leg group
21 (13 M)
   Leg group
64.5 (9.7)
  Leg group
18 right
  Leg group
TACI = 17
PACI = 13
LACI = 1
POCI = 0
unsure = 0
  Leg group
7.0 (2.5)
  Leg group
5 by 20 weeks
5 by 26 weeks
6 by 52 weeks
Partridge 2000 Single centre
Observer- blind
RCT
60 54 76.5 (range 60 - 90) 53 right No data provided in paper No data provided in paper 4 by 6 weeks
11 by 6 months
2 by 6 weeks
10 by 6 months
   (52 M)           
Rodgers 2003 Single centre
Observer- blind
RCT
61 (30 M) 62 (28 M) Median 75 (no range provided) Median 74 (no range provided) 35 right 34 right TACI = 13
PACI = 17
LACI = 29
POCI = 2
unsure = 0
TACI = 8
PACI = 17
LACI = 34
POCI = 3
unsure = 0
Median of 5 days after stroke 10 by 3 months
13 by 6 months
8 by 3 months
14 by 6 months