Figure 3
From: The VHL-dependent regulation of microRNAs in renal cancer
miRNA expression in RCC4 + VHL cells following dimethyloxalylglycine (DMOG) treatment. Expression of VHL-regulated miRNAs in RCC4 + VHL cells in response to DMOG treatment was assessed by qPCR. (a) Expression of miR-31, miR-21 and let-7i is unchanged in response to DMOG treatment. (b) Expression of miR-210, miR-155 and miR-193b is increased upon treatment with DMOG in RCC4 + VHL cells (P = 0.05), but the expression of miR-17, miR-18a and miR-20a is unchanged. The expression of the miRNAs was normalised to RNU6B. The mean ± SEM of three independent cell cultures is shown, and each sample was assayed in triplicate.