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Table 1 Multiplicity of any category of metastasisa)

From: The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model

     Average No. of organs with metastasis except
for lymph nodesb)
Groups Number of mice examined Total no. of organs with metastasis Average no. of organs with metastasis/mouseb) Lungs Ovaries Kidneys Adrenals Others
pVec 9 156 16.3 ± 3.3 2.0 ± 0.0 1.9 ± 0.3 1.6 ± 0.5 1.3 ± 0.9 0.0 ± 0.0
pesVEGFR-2 10 106 9.9 ± 4.1** 1.5 ± 0.8 1.8 ± 0.6 1.1 ± 1.0 1.6 ± 0.8 0.1 ± 0.3c)
pEndo 9 6 0.7 ± 1.1**† 0.0 ± 0.0**† 0.0 ± 0.0 **† 0.0 ± 0.0**† 0.3 ± 0.7 *† 0.1 ±0.3d)
  1. *P < 0.05; **P < 0.01 as compared with pVec values.
  2. P < 0.01 as compared with pesVEGFR-2 values.
  3. a) With respect to bilateral organs, one in unilateral metastasis and two in bilateral metastasis were counted.
  4. b) Values are mean ± SD.
  5. c) Metastasis to uterus.
  6. d) Metastasis to subcutis.