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Table 2 Clinical trials of anticancer drugs using nanocarriersa

From: Advances in the field of nanooncology

Compound

Nanocarrier

Trial stage

CPX-1 irinotecan

Liposome

Phase I [11]

LE-SN38 irinotecan

Liposome

Phase II colorectal cancer

MCC465 doxorubicin

mAb-liposome

Phase I [12]

NC-6004 cisplatin

Micelle

Phase II [13]

NK105 paclitaxel

Micelle

Phase II

NK911 doxorubicin

Micelle

Phase I

PK1 doxorubicin

HPMA copolymer

Phase II/III [14]

SP1049C doxorubicin

Micelle

Phase III [15]

  1. amAb, monoclonal antibody; HPMA, N-(2-hydroxypropyl)methacrylamide. Reproduced by permission © Jain PharmaBiotech. References to clinical trials are given in section "Current clinical trials using nanobiotechnology for cancer" of the main article.
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BMC Medicine

ISSN: 1741-7015

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