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Table 3 Classification of nanobiotechnology approaches to drug delivery in cancera

From: Advances in the field of nanooncology

Approach Examples
Nanoparticles Nanoparticle formulations of anticancer drugs, for example, paclitaxel
Exosomes for cancer drug delivery Dexosomes (exosomes produced by dendritic cells) as cancer vaccines
Nanoencapsulation and enclosure of anticancer drugs Enclosing drugs in lipid nanocapsules
  Encapsulating drugs in hydrogel nanoparticles
  Micelles for drug delivery in cancer
Targeted delivery of anticancer therapy Targeted drug delivery with nanoparticles
  Pegylated nanoliposomal formulation
  Folate-linked nanoparticles
  Carbon magnetic nanoparticles for targeted drug delivery
  Nanoparticle-aptamer bioconjugates
  Nanodroplets for site-specific cancer treatment
  Lipid-based nanocarriers
  Targeted antiangiogenic therapy using nanoparticles
  Nanoparticles for delivery of drugs to brain tumors
Combination of nanoparticles with radiotherapy Combination with boron neutron capture therapy
  Nanoengineered silicon for brachytherapy
Combination with physical modalities of cancer therapy Combination with laser ablation of tumors
  Combination with photodynamic therapy
  Combination with thermal ablation
  Combination with ultrasound
Nanoparticle-mediated gene therapy p53 gene therapy of cancer
  Immunolipoplex for delivery of p53 gene
  Intravenous delivery of FUS1 gene
Combination of diagnostics and therapeutics Nanoshells as adjuncts to thermal tumor ablation
  Perfluorocarbon nanoparticles
  Nanocomposite devices
  1. aFrom Jain KK: The Handbook of Nanomedicine, Totowa, NJ: Humana/Springer; 2008 (reproduced by permission). © Jain PharmaBiotech.