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Table 2 Demographic, physical and medical characteristics of the patients included in the study

From: Increased plasma soluble endoglin levels as an indicator of cardiovascular alterations in hypertensive and diabetic patients

  Total DIA without HYP DIA with HYP HYP without DIA Controls
Number 288 22 42 159 65
Age (yr) 54.90 ± 11.68 53.27 ± 12.74 62.17 ± 8.03 56.69 ± 11.08 48.75 ± 11.22
Male sex (%) 62.29 81.81a 66.67a 62.78 53.85
Body mass index (kg/m2) 28.32 ± 4.26 28.71 ± 4.99 30.33 ± 4.86 28.68 ± 3.93 26.82 ± 3.29
Endoglin (ng/mL) 5.04 ± 1.05 5.02 ± 0.98 4.88 ± 1.20 4.39 ± 1.04 5.21 ± 1.10
Basal glycemia (mg/dL) 98.76 ± 30.77 121.22 ± 30.03b,e 132.56 ± 45.52b,e 88.45 ± 11.49 84.47 ± 9.04
HbA1c (%) 5.42 ± 1.05 6.72 ± 1.07b,e 6.80 ± 1.30b,e 5.03 ± 0.45 4.91 ± 0.45
Systolic blood pressure (mmHg) 125.89 ± 12.72 121.34 ± 8.37 126.20 ± 14.21c 127.03 ± 13.94c 123.69 ± 9.52
Diastolic blood pressure (mmHg) 77.05 ± 9.43 73.38 ± 6.08 72.78 ± 9.11a,d 76.82 ± 9.88c 77.65 ± 7.65
Heart rate (beats/min) 71.96 ± 10.56 75.11 ± 11.29 72.51 ± 10.28 71.08 ± 11.06c 72.77 ± 10.31
Leukocytes (103 cells/μL) 6.70 ± 1.95 7.35 ± 2.90a 7.23 ± 1.94a 6.71 ± 1.96a 6.08 ± 1.03
Neutrophils (103 cells/μL) 3.52 ± 1.33 4.06 ± 2.30a 3.76 ± 1.32a 3.52 ± 1.25 3.17 ± 0.93
Lymphocytes (103 cells/μL) 2.41 ± 0.74 2.49 ± 0.61 2.71 ± 0.77 2.42 ± 0.83 2.23 ± 0.52
Monocytes (103 cells/μL) 0.54 ± 0.26 0.56 ± 0.19 0.58 ± 1.18 0.55 ± 0.32 0.47 ± 0.15
Eosinophils (103 cells/μL) 0.21 ± 0.22 0.19 ± 0.10 0.24 ± 0.17 0.23 ± 0.28 0.18 ± 0.11
Basophils (103 cells/μL) 0.04 ± 0.03 0.04 ± 0.02 0.03 ± 0.02 0.04 ± 0.03 0.03 ± 0.03
Smokers (%) 24.92 36.36 16.67 26.81 24.61
High-density lipoproteins (mg/dL) 52.35 ± 12.42 46.27 ± 8.85a,d 47.43 ± 9.74a,d 53.50 ± 12.41 54.13 ± 13.51
Low-density lipoproteins (mg/dL) 125.80 ± 32.67 113.72 ± 27.18a 105.63 ± 25.52a,d 131.43 ± 34.14c 127.13 ± 28.74
Alcohol consumption (U/wk) 11.30 ± 20.33 9.79 ± 15.82 12.70 ± 20.94 12.21 ± 23.45 10.15 ± 18.06
Daily physical activity (%) 34.75 31.82 57.14a 34.78 26.15
FPACD (%) 15.08 9.09 30.95a,c,d 13.77 9.23
  1. Data are expressed as means ± standard deviation or percentage. DIA, patients with diabetes; HbA1c, glycosylated hemoglobin; HYP, patients with hypertension; FPACD, family premature antecedents of cardiovascular disease in first-degree relatives. aStatistically significant differences (P < 0.05) vs. control group; b P < 0.0001 vs. control group; c P < 0.05 vs. DIA without HYP; d P < 0.05 vs. HYP without DIA; e P < 0.0001 vs. HYP without DIA.