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Table 4 Results from the replication cohort

From: Obesity related methylation changes in DNA of peripheral blood leukocytes

Gene

ID

Dis. to TSS

Average

Case/Con. (%)

Difference (%)

P

Age adjusted

P

UBASH3A

13517

-156

45.1/41.8

3.30

0.0019

0.008

TRIM3

---

-357

8.58/8.98

-0.40

0.3128

0.059

 

17029

-348

8.76/9.97

-1.21

0.0004

0.001

 

19207

-331

6.91/7.93

-1.02

0.0050

0.022

CTSZ

23241

-292

16.5/17.7

-1.20

0.0953

0.271

 

---

-279

27.8/29.1

-1.30

0.8425

0.798

HIPK3

---

375

48.0/55.3

-7.30

0.0184

0.061

 

25599

390

49.8/57.1

-7.30

0.0135

0.050

 

---

422

39.8/45.8

-6.00

0.0164

0.070

 

---

438

42.5/49.0

-6.50

0.0173

0.061

CDH5

8829

-243

30.3/33.4

-3.10

0.0450

0.092

CREB3L3

---

30

3.23/2.85

0.38

0.7188

0.828

 

23739

42

18.7/21.6

-2.90

0.3251

0.288

 

---

48

18.5/22.3

-3.80

0.1549

0.174

  1. ID, ID from Illumina HumanMethylation27 BeadChip
  2. Dis. to TSS, Distance to the Transcription Start Site.
  3. The targeted CpG sites are highlighted in bold.