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Table 1 Distribution of analyzed variables according to diagnostic group and unadjusted Odds Ratio over the derivation cohort.

From: Ruling out coronary heart disease in primary care patients with chest pain: a clinical prediction score

Variables

Validation

cohort

Derivation

cohort

 

(n = 774)

All

(n = 661)

CHD group

(n= 85)

Non-CHD group

(n= 576)

OR(unadjusted)

(95% CI)

 

%

%

n (%)

n (%)

 

Gender (Male)

42.0%

47.5%

43 (50.6%)

271 (47.0%)

1.2 (0.7 to 1.8)

Age-gender categories

     

   M < 55 yr or F < 65 yr

48.4%

57.8%

6 (7.1%)

376 (65.3%)

1

   M 55 to 64 yr or F 65 to 74 yr

26.0%

14.1%

17 (20.0%)

83 (14.4%)

12.8 (4.9 to 33.5)

   M ≥ 65 yr or F ≥ 75 yr

25.6%

27.1%

62 (72.9%)

117 (20.3%)

33.2 (14.0 to 78.7)

Known CVR

     

   None

21.2%

34.5%

2 (2.3%)

226 (39.2%)

1

   1-2

53.2%

50.5%

46 (54.1%)

288 (50.0%)

18.1 (4.3 to 15.8)

   ≥3

25.6%

15.0%

37 (43.5%)

62 (10.8%)

67.4 (15.8 to 287.6)

Previous history of CVD

22.0%

18.2%

62 (72.9%)

58 (10.1%)

24.1 (12.5 to 46.4)

Characteristic of the pain

     

   Duration 1 to 60 minutes

42.6%

35.2%

66 (77.6%)

167 (29.0%)

8.5 (4.8 to 15.1)

   Increasing on exertion

19.8%

21.3%

37 (43.5%)

104 (18.1%)

3.5 (2.1 to 5.7)

   Substernal area pain

57.5%

16.3%

43 (50.6%)

65 (11.3%)

8.0 (4.7 to 13.7)

   No tenderness on palpation

57.0%

54.3%

74 (87.1%)

285 (49.5%)

6.9 (3.5 to 13.5)

   Sudden excruciating pain

n/a

50.1%

34 (40.0%)

297 (51.6%)

0.63 (0.39 to 1.0)

   Oppressive pain

43.4%

36.5%

56 (65.9%)

185 (32.1%)

4.1 (2.5 to 6.7)

   Irradiation

14.0%

9.1%

8 (9.4%)

52 (9.0%)

1.0 (0.5 to 2.3)

   Not position dependant

n/a

75.8%

77 (90.6%)

424 (73.6%)

3.5 (1.6 to 7.4)

   Not increased with breathing

78.2%

76.5%

80 (94.1%)

426 (74.0%)

5.6 (2.2 to 14.4)

Digestive symptoms

 

29.0%

24 (28.2%)

168 (29.2%)

0.96 (0.58 to 1.6)

Context

     

   Known patient

91.3%

91.1%

80 (94.1%)

522 (90.6%)

1.7 (0.64 to 4.3)

   New complaint

n/a

48.8%

19/83 (22.9%)

295/561 (52.6%)

0.27 (0.15 to 0.46)

   Emergency

n/a

29.1%

19 (22.3%)

173/574 (30.1%)

0.67 (0.39 to 1.1)

   Principle complaint

89.3%

52.8%

42/84 (50.0%)

305/573 (53.2%)

0.88 (0.56 to 1.4)

   CVR status unknown (no lab)

n/a

4.8%

2 (2.3%)

30 (5.2%)

0.44 (0.1 to 1. 9)

  1. CHD = coronary heart disease; CVD = cardiovascular disease; CVR = cardiovascular risk; OR = odds ratio