Table 2 Odds ratios for breast cancer according to duration of SSRI use during exposure time windows
Exposure time window a | No. of SSRI prescriptions | Cases (n = 1,701) | Controls (n = 17,017) | Unadjusted OR b (95% CI) | Adjusted OR c (95% CI) | ||
|---|---|---|---|---|---|---|---|
n | (%) | n | (%) | ||||
≥2 years | No use d (reference) | 1,442 | (84.8) | 14,415 | (84.7) | 1.00 | 1.00 |
1 to 35 | 215 | (12.6) | 2,178 | (12.8) | 0.99 (0.85, 1.15) | 0.98 (0.84, 1.14) | |
≥36 | 44 | (2.6) | 424 | (2.5) | 1.04 (0.76, 1.42) | 1.03 (0.75, 1.41) | |
2 to 7 years | No use d (reference) | 1,512 | (88.9) | 15,122 | (88.9) | 1.00 | 1.00 |
1 to 35 | 157 | (9.2) | 1,614 | (9.5) | 0.97 (0.82, 1.16) | 0.97 (0.82, 1.15) | |
≥36 | 32 | (1.9) | 281 | (1.7) | 1.14 (0.79, 1.65) | 1.13 (0.78, 1.64) | |
>7 years | No use d (reference) | 1,556 | (91.5) | 15,528 | (91.3) | 1.00 | 1.00 |
1 to 23 | 127 | (7.5) | 1,266 | (7.4) | 1.00 (0.83, 1.21) | 1.00 (0.82, 1.21) | |
≥24 | 18 | (1.0) | 223 | (1.3) | 0.81 (0.50, 1.31) | 0.80 (0.49, 1.29) | |