A functional tandem-repeats polymorphism in the downstream of TERTis associated with the risk of nasopharyngeal carcinoma in Chinese population

Table 3 Distributions of genotypes of the MNS16A between the subgroups of cases^a with different progression of nasopharyngeal carcinoma (NPC)

NPC stage	LL ^bn (%)	SL+ SS ^b, n (%)	χ^2c	P
Clinical
I	36 (90. 0)	2 (10. 0)	1. 554	0. 21
II	334 (89. 8)	38 (10. 2)
III	212 (90. 2)	23 (9. 8)
IV	143 (93. 5)	10 (6. 5)
Tumor (T)			3. 314	0. 069
T1	151 (91. 5)	14 (8. 5)
T2	356 (89. 9)	40 (10. 1)
T3	139 (89. 7)	16 (10. 3)
T4	79 (96. 3)	3 (3. 7)
Node(N)			0. 667	0. 41
N0	148 (89. 2)	18 (10. 8)
N1	350 (91. 1)	34 (8. 9)
N2	156 (90. 7)	16 (9. 3)
N3	71 (93. 4)	5 (6. 6)
Metastasis(M)			0. 000	1. 00
M0	708 (90. 9)	71 (9. 1)
M1	17 (89. 5)	2 (10. 5)

^aOwing to genotyping failure, the actual sample size of the cases was 798.
^b L allele, 302 or 333 bp; S allele, 243 or 272 bp.
^cComparisons of genotype distributions between the different subgroups were performed using the χ² test. The degrees of freedom for the clinical, T and N stages is 3, and for the M stage is 1

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