From: Closed-loop insulin delivery for treatment of type 1 diabetes
Objective | Insulin-delivery modulation |
---|---|
Reduce severity and/or duration of hypoglycemia | Suspension of insulin delivery at hypoglycemia (low glucose suspend) |
Hypoglycemia prevention | Pre-emptive suspension/reduction of insulin delivery before hypoglycemia occurs |
Control to range | Modulation (increase or decrease) of insulin delivery outside target range to limit hypoglycemia and hyperglycemic excursions |
Overnight glucose control | Modulation of insulin delivery for nocturnal glucose control; lifestyle disturbances have limited effect |
Closed-loop system with meal/exercise announcement | Modulation of insulin delivery after meals using boluses administered by patient with announcement of these, and exercise to the algorithm |
Fully closed-loop system | Modulation of insulin delivery when the control algorithm is unaware of meals, exercise, stress and other lifestyle disturbances that affect glucose control; glucagon may be coadministered to reduce risk of hypoglycemia |