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Table 2 Summary estimates of sensitivity and specificity calculated by a bivariate random-effects model

From: The Alvarado score for predicting acute appendicitis: a systematic review

  Studies n Sensitivity
(95% CI)
Variance logit (sensitivity) Specificity (95% CI) Variance logit (specificity)
Observation/
Admission
(Cut point 5)
All studies 28 0.99 (0.97 to 0.99) 3.37 0.43 (0.36 to 0.51) 0.61
  Men 5 0.96 (0.88 to 0.99) 1.09 0.34 (0.24 to 0.47) 0.06
  Women 5 0.99 (0.92 to 0.99) 2.12 0.35 (0.14 to 0.64) 1.51
  Children* 9 0.99 (0.83 to 1.00) 8.99 0.57 (0.41 to 0.72) 0.79
Surgery
(Cut point 7)
All studies 29 0.82 (0.76 to 0.86) 0.48 0.81 (0.76 to 0.85) 0.46
  Men 6 0.88 (0.75 to 0.95) 1.15 0.57 (0.40 to 0.73) 0.44
  Women 7 0.86 (0.78 to 0.92) 0.44 0.73 (0.58 to 0.84) 0.62
  Children* 9 0.87 (0.76 to 0.93) 0.98 0.76 (0.55 to 0.89) 1.50
  1. * For the purpose of this study Children are defined as any participant under the age of 18 years of age.