Skip to main content

Table 2 Adjusted geometric mean hormone levels in three populationsa

From: Comparison of postmenopausal endogenous sex hormones among Japanese, Japanese Brazilians, and non-Japanese Brazilians

 

Japanese living in Nagano, Japan

Japanese Brazilians living in São Paulo, Brazil

Non-Japanese Brazilians living in São Paulo, Brazil

Pfor difference

Estradiol, pg/mL

    

   Age-adjusted

9.0

13.8

15.5

<0.01

   (95% CI)

(8.6 to 9.4)

(12.5 to 15.3)

(14.6 to 16.5)

 

   P a

<0.01

Reference

0.052

 

   Multivariateb

9.7

14.3

15.5

<0.01

   (95% CI)

(8.7 to 10.9)

(12.5 to 16.4)

(14.0 to 17.1)

 

   P a

<0.01

Reference

0.28

 

Bioavailable estradiol, %

    

   Age-adjusted

23.1

30.6

22.9

<0.01

   (95% CI)

(22.1 to 24.1)

(28.0 to 33.4)

(21.7 to 24.1)

 

   P a

<0.01

Reference

<0.01

 

   Multivariateb

23.7

30.2

20.6

<0.01

   (95% CI)

(21.6 to 26.0)

(27.0 to 33.8)

(19.0 to 22.3)

 

   P a

<0.01

Reference

<0.01

 

Estrone, pg/mL

    

   Age-adjusted

23.0

40.3

34.1

<0.01

   (95% CI)

(22.0 to 24.0)

(36.8 to 44.1)

(32.4 to 35.9)

 

   P a

<0.01

Reference

<0.01

 

   Multivariateb

23.8

41.1

33.3

<0.01

   (95% CI)

(21.5 to 26.3)

(36.5 to 46.3)

(30.6 to 36.4)

 

   P a

<0.01

Reference

<0.01

 

Sex hormone-binding globulin, nM/L

    

   Age-adjusted

74.1

54.3

60.2

<0.01

   (95% CI)

(69.4 to 79.1)

(47.5 to 62.0)

(55.8 to 65.1)

 

   P a

<0.01

Reference

0.18

 

   Multivariateb

68.4

53.0

70.7

0.01

   (95% CI)

(59.5 to 78.5)

(44.9 to 62.4)

(62.6 to 79.7)

 

   P a

<0.01

Reference

<0.01

 

Androstenedione, ng/mL

    

   Age-adjusted

0.65

0.56

1.04

<0.01

   (95% CI)

(0.60 to 0.70)

(0.47 to 0.66)

(0.95 to 1.15)

 

   P a

0.12

Reference

<0.01

 

   Multivariateb

0.73

0.60

1.00

<0.01

   (95% CI)

(0.61 to 0.88)

(0.48 to 0.76)

(0.85 to 1.18)

 

   P a

0.06

Reference

<0.01

 

DHEAS, μg/dL

    

   Age-adjusted

50.6

58.0

44.5

0.03

   (95% CI)

(46.3 to 55.4)

(48.2 to 69.8)

(40.0 to 49.4)

 

   P a

0.19

Reference

0.01

 

   Multivariateb

57.2

63.1

46.7

0.04

   (95% CI)

(46.6 to 70.2)

(49.4 to 80.6)

(39.2 to 55.8)

 

   P a

0.38

Reference

0.02

 

Testosterone, ng/mL

    

   Age-adjusted

0.02

0.11

0.18

<0.01

   (95% CI)

(0.02 to 0.03)

(0.07 to 0.17)

(0.14 to 0.24)

 

   P a

<0.01

Reference

0.06

 

   Multivariateb

0.03

0.10

0.14

<0.01

   (95% CI)

(0.02 to 0.04)

(0.06 to 0.20)

(0.09 to 0.22)

 

   P a

<0.01

Reference

0.38

 

Free testosterone, pg/mL

    

   Age-adjusted

0.21

0.39

0.44

<0.01

   (95% CI)

(0.19 to 0.23)

(0.33 to 0.46)

(0.40 to 0.48)

 

   P a

<0.01

Reference

0.18

 

   Multivariateb

0.22

0.39

0.39

<0.01

   (95% CI)

(0.19 to 0.26)

(0.32 to 0.47)

(0.34 to 0.45)

 

   P a

<0.01

Reference

0.92

 
  1. DHEAS, dehyroepianrosterone sulfate; 95% CI, 95% confidence interval; a P values for comparison with Japanese Brazilians living in São Paulo, Brazil; bAdjusted for age (continuous), age at first menarche (continuous), age at menopause (continuous), number of births (0, 1, 2 or 3, 4+), age at first birth (≤22, 23 to 26, ≥27 yr, nulliparous), height (continuous), body mass index (continuous), smoking (never smokers, past smokers, current smokers), alcohol drinking (nondrinkers, occasional drinker, regular drinkers), and physical activity in past 5 years (no, ≤2 days/wk, ≥3 days/wk).
Back to article page