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Table 1 Genotype and allele distributions of the six SNPs in the MUC4 gene in Taiwanese endometriosis patients and controlsa

From: MUC4gene polymorphisms associate with endometriosis development and endometriosis-related infertility

SNPs Genotype/allele No. (%)of patients HWE No. (%)of controls HWE Pvalue OR (95% CI)
rs882605 TT 9 (7.0) 0.62 10 (7.2) 0.07 0.04 1.13 (0.43 to 3.00)
  TG 54 (42.2)   40 (28.8)    1.97 (1.17 to 3.32)b
  GG 65 (50.8)   89 (64.0)    1.00 Reference
  T 72 (28.1)   60 (21.6)   0.08 1.42 (0.96 to 2.11)
  G 184 (71.9)   218 (78.4)    1.00 Reference
rs1104760 CC 7 (5.4) 0.94 9 (6.3) 0.09 0.30 0.96 (0.33 to 2.82)
  CT 47 (36.2)   39 (27.5)    1.49 (0.89 to 2.51)
  TT 76 (58.5)   94 (66.2)    1.00 Reference
  C 61 (23.5)   57 (20.1)   0.34 1.22 (0.81 to 1.84)
  T 199 (76.5)   227 (79.9)    1.00 Reference
rs2246901 GG 8 (6.0) 0.96 10 (7.1) 0.15 0.56 0.91 (0.33 to 2.53)
  TG 49 (36.6)   43 (30.5)    1.30 (0.78 to 2.17)
  TT 77 (57.5)   88 (62.4)    1.00 reference
  G 65 (24.3)   63 (22.3)   0.60 1.11 (0.75 to 1.65)
  T 203 (75.7)   219 (77.7)    1.00 Reference
rs2258447 AA 9 (6.4) 0.37 10 (7.0) 0.07 0.70 1.02 (0.38 to 2.77)
  AG 44 (32.1)   40 (28.2)    1.25 (0.74 to 2.11)
  GG 81 (61.4)   92 (64.8)    1.00 Reference
  A 62 (22.5)   60 (21.1)   0.57 1.12 (0.75 to 1.68)
  G 206 (77.5)   224 (78.9)    1.00 Reference
rs2291652 CC 11 (8.7) 0.92 11 (8.4) 0.26 0.52 1.17 (0.46 to 2.96)
  CT 52 (40.9)   45 (34.4)    1.35 (0.81 to 2.28)
  TT 64 (50.4)   75 (57.3)    1.00 Reference
  C 74 (29.1)   67 (25.6)   0.36 1.20 (0.81 to 1.76)
  T 180 (70.9)   195 (74.4)    1.00 Reference
rs2688513 CC 8 (6.0) 0.62 10 (7.0) 0.09 0.66 0.91 (0.33 to 2.53)
  TC 45 (33.8)   41 (28.9)    1.25 (0.74 to 2.10)
  TT 80 (60.2)   91 (64.1)    1.00 Reference
  C 61 (22.9)   61 (21.5)   0.68 1.09 (0.73 to 1.63)
  T 205 (77.1)   223 (78.5)    1.00 Reference
  1. a MUC4, mucin 4 gene; SNP, single-nucleotide polymorphism; OR, odds ratio; 95% CI, 95% confidence interval; HWE, P values of deviation from the Hardy-Weinberg equilibrium constant. Allelic frequencies were determined by χ2 test using 2 × 2 contingency tables. Genotype frequencies were determined by χ2 test using 2 × 3 contingency tables. b P < 0.05 was considered statistically significant.