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Table 3 Genotype and allele distributions of SNPs in the MUC4 gene in endometriosis patients at different clinical stagesa

From: MUC4gene polymorphisms associate with endometriosis development and endometriosis-related infertility

SNP Genotype/allele No. (%) at mild stageb No. (%) at severe stagec Pvalue
rs882605 TT 0 (0.0) 7 (8.0) 0.25
  TG 2 (25.0) 41 (46.6)  
  GG 6 (75.0) 40 (45.5)  
  TT+TG 2 (25.0) 48 (54.5) 0.11
  GG 6 (75.0) 40 (45.5)  
  T 2 (12.5) 55 (31.3) 0.12
  G 14 (87.5) 121 (68.8)  
rs1104760 CC 0 (0.0) 5 (5.8) 0.05
  CT 0 (0.0) 36 (41.9)  
  TT 7 (100.0) 45 (52.3)  
  CC+CT 0 (0.0) 41 (47.7) 0.0d
  TT 7 (100.0) 45 (52.3)  
  C 0 (0.0) 46 (26.7) 0.03d
  T 14 (100.0) 126 (73.3)  
rs2688513 CC 0 (0.0) 6 (6.9) 0.04d
  CT 0 (0.0) 34 (39.1)  
  TT 8 (100.0) 47 (54.0)  
  CC+CT 0 (0.0) 40 (46.0) 0.01d
  TT 8 (100.0) 47 (54.0)  
  C 0 (0.0) 46 (26.4) 0.02d
  T 16 (100.0) 128 (73.6)  
rs2246901 GG 0 (0.0) 6 (6.8) 0.03d
  TG 0 (0.0) 36 (40.9)  
  TT 8 (100.0) 46 (52.3)  
  GG+TG 0 (0.0) 42 (47.7) 0.01d
  TT 8 (100.0) 46 (52.3)  
  G 0 (0.0) 48 (27.3) 0.02d
  T 16 (100.0) 128 (72.7)  
rs2258447 AA 0 (0.0) 7 (7.9) 0.08
  AG 0 (0.0) 32 (36.0)  
  GG 7 (100.0) 50 (56.2)  
  AA+AG 0 (0.0) 39 (43.8) 0.02d
  GG 7 (100.0) 50 (56.2)  
  A 0 (0.0) 46 (25.8) 0.03d
  G 14 (100.0) 132 (74.2)  
rs2291652 CC 0 (0.0) 7 (8.3) 0.61
  CT 2 (33.3) 36 (42.9)  
  TT 4 (66.7) 41 (48.8)  
  CC+CT 2 (33.3) 43 (51.2) 0.40
  TT 4 (66.7) 41 (48.8)  
  C 2 (16.7) 50 (29.8) 0.33
  T 10 (83.3) 118 (70.2)  
  1. aSNP, single-nucleotide polymorphism; MUC4, mucin 4 gene. Allelic frequencies were determined by Fisher's exact test using 2 × 2 contingency tables. Genotype frequencies were determined by Fisher's exact test using 2 × 3 contingency tables. bMild stage, patients at clinical stage1 or stage 2; cSevere stage, patients at clinical stage 3 or stage 4; d P < 0.05 was considered statistically significant.