SNP | Genotype/allele | No. (%) at mild stageb | No. (%) at severe stagec | Pvalue | ||
---|---|---|---|---|---|---|
rs882605 | TT | 0 | (0.0) | 7 | (8.0) | 0.25 |
 | TG | 2 | (25.0) | 41 | (46.6) |  |
 | GG | 6 | (75.0) | 40 | (45.5) |  |
 | TT+TG | 2 | (25.0) | 48 | (54.5) | 0.11 |
 | GG | 6 | (75.0) | 40 | (45.5) |  |
 | T | 2 | (12.5) | 55 | (31.3) | 0.12 |
 | G | 14 | (87.5) | 121 | (68.8) |  |
rs1104760 | CC | 0 | (0.0) | 5 | (5.8) | 0.05 |
 | CT | 0 | (0.0) | 36 | (41.9) |  |
 | TT | 7 | (100.0) | 45 | (52.3) |  |
 | CC+CT | 0 | (0.0) | 41 | (47.7) | 0.0d |
 | TT | 7 | (100.0) | 45 | (52.3) |  |
 | C | 0 | (0.0) | 46 | (26.7) | 0.03d |
 | T | 14 | (100.0) | 126 | (73.3) |  |
rs2688513 | CC | 0 | (0.0) | 6 | (6.9) | 0.04d |
 | CT | 0 | (0.0) | 34 | (39.1) |  |
 | TT | 8 | (100.0) | 47 | (54.0) |  |
 | CC+CT | 0 | (0.0) | 40 | (46.0) | 0.01d |
 | TT | 8 | (100.0) | 47 | (54.0) |  |
 | C | 0 | (0.0) | 46 | (26.4) | 0.02d |
 | T | 16 | (100.0) | 128 | (73.6) |  |
rs2246901 | GG | 0 | (0.0) | 6 | (6.8) | 0.03d |
 | TG | 0 | (0.0) | 36 | (40.9) |  |
 | TT | 8 | (100.0) | 46 | (52.3) |  |
 | GG+TG | 0 | (0.0) | 42 | (47.7) | 0.01d |
 | TT | 8 | (100.0) | 46 | (52.3) |  |
 | G | 0 | (0.0) | 48 | (27.3) | 0.02d |
 | T | 16 | (100.0) | 128 | (72.7) |  |
rs2258447 | AA | 0 | (0.0) | 7 | (7.9) | 0.08 |
 | AG | 0 | (0.0) | 32 | (36.0) |  |
 | GG | 7 | (100.0) | 50 | (56.2) |  |
 | AA+AG | 0 | (0.0) | 39 | (43.8) | 0.02d |
 | GG | 7 | (100.0) | 50 | (56.2) |  |
 | A | 0 | (0.0) | 46 | (25.8) | 0.03d |
 | G | 14 | (100.0) | 132 | (74.2) |  |
rs2291652 | CC | 0 | (0.0) | 7 | (8.3) | 0.61 |
 | CT | 2 | (33.3) | 36 | (42.9) |  |
 | TT | 4 | (66.7) | 41 | (48.8) |  |
 | CC+CT | 2 | (33.3) | 43 | (51.2) | 0.40 |
 | TT | 4 | (66.7) | 41 | (48.8) |  |
 | C | 2 | (16.7) | 50 | (29.8) | 0.33 |
 | T | 10 | (83.3) | 118 | (70.2) |  |