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Table 4 Genotype and allele distributions of the six SNPs in the MUC4 gene in endometriosis patients with different reproductive abilitya

From: MUC4gene polymorphisms associate with endometriosis development and endometriosis-related infertility

SNP Genotype/allele No. (%) infertility No. (%) noninfertility Pvalue OR (95% CI)
rs882605 TT 0 (0.0) 8 (8.7) 0.07 - -
  TG 5 (26.3) 42 (45.7)   0.36 (0.12 to 1.08)
  GG 14 (73.7) 42 (45.7)   1.00 Reference
  T 5 (13.2) 58 (31.5) 0.03b 0.33 (0.12 to 0.89)
  G 33 (86.8) 126 (68.5)   1.00 Reference
rs1104760 CC 0 (0.0) 6 (6.3) 0.41 - -
  CT 4 (25.0) 37 (38.5)   0.48 (0.14 to 1.60)
  TT 12 (75.0) 53 (55.2)   1.00 Reference
  C 4 (12.5) 49 (25.5) 0.12 0.42 (0.14 to 1.25)
  T 28 (87.5) 143 (74.5)   1.00 Reference
rs2688513 CC 0 (0.0) 7 (7.4) 0.32 - -
  TC 5 (25.0) 34 (36.2)   0.52 (0.17 to 1.56)
  TT 15 (75.0) 53 (56.4)   1.00 Reference
  C 5 (12.5) 48 (25.5) 0.09 0.42 (0.15 to 1.12)
  T 35 (87.5) 140 (74.5)   1.00 Reference
rs2246901 GG 0 (0.0) 7 (7.4) 0.25 - -
  TG 5 (25.0) 37 (38.9)   0.46 (0.15 to 1.38)
  TT 15 (75.0) 51 (53.7)   1.00 Reference
  G 5 (12.5) 51 (26.8) 0.06 0.39 (0.14 to 1.05)
  T 35 (87.5) 139 (73.2)   1.00 Reference
rs2258447 AA 1 (5.0) 7 (7.3) 0.41 0.53 (0.05 to 5.53)
  AG 4 (20.0) 33 (34.4)   0.45 (0.14 to 1.48)
  GG 15 (75.0) 56 (58.3)   1.00 Reference
  A 6 (15.0) 47 (24.5) 0.22 0.54 (0.22 to 1.38)
  G 34 (85.0) 145 (75.5)   1.00 Reference
rs2291652 CC 0 (0.0) 7 (7.8) 0.29 - -
  CT 7 (35.0) 40 (44.4)   0.58 (0.21 to 1.60)
  TT 13 (65.0) 43 (47.8)   1.00 Reference
  C 7 (17.5) 54 (30.0) 0.12 0.49 (0.21 to 1.19)
  T 33 (82.5) 126 (70.0)   1.00 Reference
  1. aSNP, single-nucleotide polymorphism; MUC4, mucin 4 gene; OR, odds ratio; 95% CI, 95% confidence interval. Allelic frequencies were determined by Fisher's exact test using 2 × 2 contingency tables. Genotype frequencies were determined by Fisher's exact test using 2 × 3 contingency tables. b P < 0.05 was considered statistically significant.