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Table 1 Pooled microdialysis data and intracranial pressureaa

From: Analyses of cerebral microdialysis in patients with traumatic brain injury: relations to intracranial pressure, cerebral perfusion pressure and catheter placement

   

ICP, mmHg

 

Microdialysis data

< 15

15 to 20

20 to 25

25 to 30

> 30

   Pericontusional

     

   Glucose, mM/l

2.2 ± 1.6

1.6 ± 1.0

1.3 ± 1.3

1.9 ± 2.0

0.9 ± 1.5

   Lactate, mM/l

5.0 ± 2.7

5.4 ± 2.7

5.7 ± 2.4

5.3 ± 3.0

6.3 ± 5.7

   Pyruvate, μM/l

176 ± 87

161 ± 82

148 ± 83

209 ± 234

195 ± 221

   Glycerol, μM/l

256 ± 397

260 ± 418

240 ± 273

181 ± 190

284 ± 361

   LP ratio

34 ± 39

49 ± 84

74 ± 122

62 ± 116

75 ± 158

   LG ratio

5.2 ± 12

8.1 ± 17

18 ± 28

24 ± 41

51 ± 65

Number of samples

(n = 64 patients)

3,059

1,534

816

153

83

Nonpericontusional

     

   Glucose, mM/l

2.2 ± 1.5

1.5 ± 1.1

1.4 ± 1.2

1.0 ± 1.0

1.9 ± 2.2

   Lactate, mM/l

3.7 ± 1.8

4.4 ± 2.8

5.2 ± 2.7

6.4 ± 2.9

5.0 ± 2.6

   Pyruvate, μM/l

162 ± 60

150 ± 64

161 ± 64

170 ± 79

161 ± 110

   Glycerol, μM/l

171 ± 207

337 ± 450

414 ± 513

735 ± 763

1,029 ± 907

   LP ratio

23 ± 9.0

31 ± 24

36 ± 30

42 ± 23

36 ± 20

   LG ratio

4.5 ± 9.8

8.2 ± 20

12 ± 24

16 ± 11

10 ± 12

Number of samples

(n = 26 patients)

903

570

220

34

4

  1. aData are binned to levels of intracranial pressure (ICP), including the lactate:pyruvate (LP) and lactate:glucose (LG) ratios, from 90 catheters (90 patients), in pericontusional and nonpericontusional locations. Data are expressed as means ± standard deviation (SD).
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BMC Medicine

ISSN: 1741-7015

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