Skip to main content

Table 1 Demographic, clinical and venous hemodynamic characteristics of relapsing remitting MS patients and healthy controlsa

From: Hypoperfusion of brain parenchyma is associated with the severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis: a cross-sectional preliminary report

Characteristic MS patients
(n= 16)
Healthy controls
(n= 8)
Pvalue
Female sex, n (%) 10 (63%) 6 (75%) NS
Mean age, yr (±SD) 36.1 ± 7.3 33.1 ± 7.3 NS
Disease duration, mean (±SD) 7.5 ± 1.9   
Age at diagnosis, mean (±SD) 35.8 ± 9.2   
Expanded Disability Status Scale, mean (±SD) and median (range) 2.4 ± 0.9, 2.5 (1.0 to 3.5)   
Mean Multiple Sclerosis Functional Composite score (±SD) -2.5 ± 0.03 -2.5 ± 0.02 NS
Mean treatment duration, yr (±SD) 4.3 ± 3.4   
Distribution of VH criteria, n (%)    
   VH1 12 (75%) 0 (0%) <0.001
   VH2 14 (88%) 0 (0%)  
   VH3 14 (88%) 1 (13%)  
   VH4 13 (81%) 0 (0%)  
   VH5 8 (50%) 0 (0%)  
   Mean number of VH criteria (±SD) 3.8 ± 0.23 0.12 ± 0.35 <0.001
   Mean VHISS (±SD) 8.9 ± 2.8 0 ± 0 <0.001
  1. aMS, multiple sclerosis; VH, venous hemodynamic; SD, standard deviation; VHISS, venous hemodynamic insufficiency severity score; NS, nonsignificant. The differences between MS patients and healthy controls were assessed using the Student's t-test, Fisher's exact test and Mann-Whitney rank-sum test.