Recent advances in the treatment of Pseudomonas aeruginosainfections in cystic fibrosis

Table 1 Important properties of mucoid and nonmucoid phenotypes of Pseudomonas aeruginos a in the respiratory tract of cystic fibrosis patients^a

Property	Mucoid phenotype	Nonmucoid phenotype
Location in the lungs	Respiratory zone and conductive zone in sputum	Conductive zone in sputum
Biofilm formation in vitro	Yes	Yes
Biofilm formation in vivo	Yes	No
Multiply antibiotic resistance due to conventional mechanisms	Seldom	Frequent
Resistance (tolerance) due to biofilm properties	Yes	No
Responsible for lung tissue damage	Yes	No
Induces pronounced antibody response	Yes	No

ISSN: 1741-7015