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Table 2 Studies according to the type of intervention.

From: Risk of infection in patients with lymphoma receiving rituximab: systematic review and meta-analysis

Intervention

Study

Intervention arm a

Adjuvant therapies b

 

Type of CHT

N. Cycles

R courses

G-CSF

AI prophylaxis

RTX

Other

Aviles 2007a

CEOP

6

6

Discretionary

NR

No

No

Aviles 2007b

CEOP

6

6

Not reported

Aviles 2010

ESHAP

6

6

To all

No

No

No

Buske 2009

CHOP 21

4 to 8

4 to 8

Not reported

Coiffier 2002

CHOP 21

8

8

Discretionary

NR

No

No

Eve 2009

FC

8

8

NR

PCP + VZV

No

No

Forstpointner 2004

FCM

4

4

Not reported

Habermann 2006

CHOP 21

6 to 8

4 to 5

Discretionary

NR

No

M

Herold 2007

MCP

8

8

Not reported

Hiddemann 2005

CHOP 21

6 to 8

6 to 8

Not reported

Kaplan 2005

CHOP 21

3 to 6

3 to 6

To all

PCP

Discretionary

M + ART

Lenz 2005

CHOP 21

6

6

Not reported

Marcus 2005

CVP

8

8

Not reported

Pfreundschuh 2008a

CHOP 14

6

8

To all

No

No

Pre-O

Pfreundschuh 2008b

CHOP 14

8

8

To all

No

No

Pre-O

Robak 2010

FC

6

6

Discretionary

No

No

No

van Oers 2006

CHOP 21

3 to 6

3 to 6

Not reported

  1. Detailed protocol reported in additional file 6. a) This describes the type of therapy for intervention arm (patients in control arm received the same therapy apart from rituximab); b) This includes all reported non randomized therapies. AI prophylaxis = anti-infective prophylaxis; ART = antiretroviral therapy; C = chemotherapy; -CSF = granulocyte colony stimulating factor; GRTX = radio therapy; M = meningeal prophylaxis with methotrexate; N. cycles = number of cycles of scheduled therapy; NR = not reported; PCP = prophylaxis against P. jaroviecy; Pre-O = pre-treatment with single dose 1 mg vincristine and 100 mg prednisone orally for seven days; R course = number of cycles of scheduled rituximab course; VZV = prophylaxis against Varicella zoster virus