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Table 3 Stratified analysis between methotrexate (MTX) use and elevated ATP-binding cassette transporter A1 (ABCA1) and 27-hydroxylase expression in study subjects

From: Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment

Category    Logistic regression
  Low (≤median) High (>median) OR (95% CI) Pvalue
ABCA1/18S:     
MTX     
No (n = 32) 20 (62.5%) 12 (37.5%) 1.00  
Yes (n = 67) 31 (46%) 36 (54%) 1.94 (0.82 to 4.58) 0.13
27-Hydroxylase/18S:     
MTX     
No (n = 32) 21 (66%) 11 (34%) 1.00  
Yes (n = 67) 29 (43%) 38 (57%) 2.50 (1.04 to 6.01) 0.038
  1. Values represent N (%). Logistic regression results are expressed as OR (95% confidence interval) (n = 99).