Table 3 Stratified analysis between methotrexate (MTX) use and elevated ATP-binding cassette transporter A1 (ABCA1) and 27-hydroxylase expression in study subjects
Category | Â | Â | Logistic regression | |
|---|---|---|---|---|
|  | Low (≤median) | High (>median) | OR (95% CI) | Pvalue |
ABCA1/18S: | Â | Â | Â | Â |
MTX | Â | Â | Â | Â |
No (n = 32) | 20 (62.5%) | 12 (37.5%) | 1.00 | Â |
Yes (n = 67) | 31 (46%) | 36 (54%) | 1.94 (0.82 to 4.58) | 0.13 |
27-Hydroxylase/18S: | Â | Â | Â | Â |
MTX | Â | Â | Â | Â |
No (n = 32) | 21 (66%) | 11 (34%) | 1.00 | Â |
Yes (n = 67) | 29 (43%) | 38 (57%) | 2.50 (1.04 to 6.01) | 0.038 |