L-lysine blood conc (μmol/l)
|
196 ± 14 (201 ± 15)
|
401 ± 74 (363 ± 64)
|
195 ± 13 (195 ± 10)
|
7.84 (6.57)
|
0.024 (0.027)
|
Symptom severity scales
| | | | | |
PANSS
| | | | | |
Positive symptoms
|
14.6 ± 0.7 (16.0 ± 1.1)
|
11.9 ± 0.6 (13.5 ± 1.3)
|
11.6 ± 0.8 (13.4 ± 1.4)
|
13.11 (12.49)
|
0.001 (0.000)
|
Negative symptoms
|
18.4 ± 2.4 (19.7 ± 2.2)
|
17.4 ± 2.2 (19.4 ± 2.2)
|
17.3 ± 2.4 (18.8 ± 2.2)
|
1.53 (0.69)
|
0.25 (0.51)
|
General symptoms
|
31.3 ± 2.5 (33.5 ± 2.5)
|
29.5 ± 1.9 (32.3 ± 2.4)
|
29.1 ± 2.0 (30.9 ± 2.0)
|
2.14 (2.84)
|
0.16 (0.09)
|
Total
|
64.3 ± 4.2 (69.2 ± 4.7)
|
58.8 ± 4.0 (65.2 ± 5.4)
|
58.0 ± 4.5 (63.1 ± 5.0)
|
13.36 (8.59)
|
0.001 (0.002)
|
GAF
|
43.8 ± 1.8 (42.0 ± 1.9)
|
46.9 ± 1.6 (45.8 ± 1.6)
|
44.1 ± 2.3 (42.8 ± 2.1)
|
4.29 (7.34)
|
0.035 (0.005)
|
CGI
|
3.63 ± 0.18 (3.80 ± 0.20)
|
3.63 ± 0.18 (3.80 ± 0.20)
|
3.50 ± 0.27 (3.70 ± 0.26)
|
1.00 (1.00)
|
0.39 (0.39)
|
Depression scale
| | | | | |
MADRS
|
8.50 ± 2.09 (9.10 ± 1.74)
|
7.50 ± 1.90 (7.90 ± 1.57)
|
8.38 ± 1.74 (8.40 ± 1.38)
|
0.54 (0.89)
|
0.59 (0.43)
|
Cognitive tests
| | | | | |
RAVLT
|
45.9 ± 4.3 (43.5 ± 4.2)
|
46.0 ± 4.6 (43.3 ± 4.4)
|
48.8 ± 3.5 (45.2 ± 4.1)
|
0.79 (0.48)
|
0.47 (0.62)
|
CPT
|
0.76 ± 0.16 (0.67 ± 0.13)
|
0.81 ± 0.13 (0.76 ± 0.12)
|
0.86 ± 0.13 (0.71 ± 0.14)
|
0.25 (0.21)
|
0.77 (0.81)
|
Trail Making Test A
|
33.8 ± 1.7 (39.2 ± 5.9)
|
31.3 ± 2.5 (39.9 ± 8.9)
|
35.3 ± 4.5 (40.8 ± 6.3)
|
0.44 (0.07)
|
0.58 (0.93)
|
Trail Making Test B
|
77.4 ± 7.2 (134 ± 56)
|
70.0 ± 5.2 (119 ± 48)
|
71.3 ± 6.4 (124 ± 50)
|
0.40 (1.61)
|
0.68 (0.24)
|
Letter and number span
|
8.13 ± 0.90 (7.00 ± 1.03)
|
9.00 ± 0.66 (8.10 ± 0.82)
|
9.13 ± 0.92 (8.50 ± 0.95)
|
0.74 (1.92)
|
0.50 (0.18)
|
Wisconsin Card Sorting
| | | | | |
Number of errors
|
33.9 ± 10.0 (31.9 ± 9.0)
|
21.0 ± 7.2 (19.7 ± 6.5)
|
24.4 ± 10.1 (23.2 ± 9.0)
|
4.91 (5.45)
|
0.024 (0.016)
|
Perseverant errors
|
20.4 ± 7.6 (19.0 ± 6.8)
|
11.5 ± 5.0 (10.7 ± 4.4)
|
14.8 ± 8.1 (13.4 ± 7.3)
|
4.46 (5.00)
|
0.032 (0.021)
|
Perseverant answers
|
23.6 ± 9.6 (21.9 ± 8.7)
|
13.1 ± 6.6 (21.1 ± 5.9)
|
17.1 ± 10.3 (15.6 ± 9.2)
|
4.77 (5.20)
|
0.026 (0.018)
|