Skip to main content

Table 2 Antibiotic prescription at initial visit (and within 48 hours of initial visit) for adult patients with acute respiratory tract infection, according to randomisation group (rapid result vs. delayed result)

From: Access to a polymerase chain reaction assay method targeting 13 respiratory viruses can reduce antibiotics: a randomised, controlled trial

Antibiotic prescription Rapid result (n= 202) Delayed result (n= 204) P
Initial antibiotic treatment, n (%) 9 (4.5) 25 (12.3) 0.005a
   At initial visit 7 (3.5) 21 (10.3)  
   After 24 to 48 hours 2 (1.0) 4 (2.0)  
   β-lactamb 4 (2.0) 13 (6.4) -
   Tetracycline 4 (2.0) 8 (3.9) -
   Macrolide 1 (0.5) 3 (1.5) -
   Quinolone - 1 (0.5) -
Patient demographics at initial antibiotic treatment, n (%)    
   Body temperature ≥38.5°C, n (%) - 4 (33.3c) -
   CRP level ≥50 mg/L, n (%) 2 (8.3d) 10 (67.0e) < 0.001a
   Duration of illness ≤5 days, n (%) 3 (3.3f) 12 (12.4f) 0.02a
   Duration of illness > 5 days, n (%) 6 (5.4) 13 (12.1) -
Patients with virus detected, n (%) 91 (45.0) 91 (44.6) -
   Antibiotics prescribed 3 (3.3g) 11 (12.1g) 0.03a
Patients with Mycoplasma pneumoniae detected, n (%) 5 (2.5) 2 (1.0) -
   Antibiotics prescribed, n 2h 2h  
Patients with Chlamydophila pneumoniae detected, n (%) 1 (0.5) -  
   Antibiotics prescribed, n 1i - -
  1. aχ2 test; bphenoxymethylpenicillin or amoxicillin with or without clavulanic acid or loracarbef; cfour (33.3%) of twelve patients; dtwo (8.3%) of twenty-four patients; e10 (67.0%) of 15 patients; fthree (3.3%) of ninety-one patients and 12 (12.4%) of 97 patients, respectively; gthree (3.3%) of ninety-one patients and 11 (12.1%) of 91 patients, respectively; hone patient received antibiotics within 24 hours and the other within 48 hours in each group, for a total of two patients in each group as indicated in table; ipatient received antibiotics within 48 hours.