Table 2 Examples of imaging techniques used in the past and that can be used in the future
Assessments | Previous functional imaging protocols | Optimized functional imaging protocols |
|---|---|---|
DA-rich graft survival and growth | 18F-DOPA PET | 18F-DOPA PET |
Patient selection | - | 18F-DOPA PET |
DA release from the graft | 11C-raclopride with challenge | 11C-raclopride with challenge |
Graft-derived 5-HT innervation and growth | - | 11C-DASB |
Graft-induced dyskinesias | - | 11C-DASB PET/18F-DOPA PET ratio 11C-DASB PET/123I-FP-CIT SPECT ratio |
Inflammatory and immune responses around the graft | - | 11C-PK11195 |
Brain activation during movement | H2 15O PET with motor execution tasks | fMRI with motor execution tasks |
Functional connectivity between brain regions | - | Resting-state fMRI |
White matter structural connectivity | - | Diffusion Tensor Imaging |