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Table 2 Input values for standardized analysis in each hypothetical country in the sub-Saharan African (SSA) region, Southeast Asian (SEA) region and Latin America and the Caribbean (LAC) region

From: Cost effectiveness of pediatric pneumococcal conjugate vaccines: a comparative assessment of decision-making tools

Model parameters Standardized values
  SSA region SEA region LAC region
Population:    
Total number of birth per year 60,477 932,115 140,414
Life expectancy at birth (in years) 59.45 70.62 72.9
Burden of disease:    
Incidence of pneumococcal pneumonia (per 100,000 per year) 1,793 1,793 1,771
Incidence of meningitis (per 100,000 per year) 10 10 18
Incidence of invasive NPNM (per 100,000 per year) 77 77 137
Incidence of otitis media (per 100,000 per year) 400 400 400
Case fatality rate of pneumococcal pneumonia 1 1 1.8
Case fatality rate of pneumococcal meningitis 20 20 36.8
Case fatality rate of invasive NPNM 10 10 20.46
Vaccine information:    
Vaccine coverage* 89% 97% 83%
Serotype coverage of pneumococcal pneumonia 60% 60% 60%
Vaccine efficacy of pneumococcal pneumonia 97.40% 97.40% 97.40%
Vaccine efficacy of pneumococcal meningitis 97.40% 97.40% 97.40%
Vaccine efficacy of pneumococcal invasive NPNM 97.40% 97.40% 97.40%
Vaccine efficacy of otitis media 57% 57% 57%
Costing information:    
Dose cost $26.35 $26.35 $26.35
  1. Standardized input of vaccine cost (US$26.35) = £16.096 (rate US$1 = £0.61) (from http://www.xe.com/ucc/) [13].
  2. NPNM = non-pneumonia non-meningitis.