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Table 4 Signature genes and their functionalities

From: Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells

Functionality

Genes from signature

Interferon signaling and interferon-induced or interferon-regulated genes

IFI35, IFIT1, IFIT3, IFITM1, MX1, OAS1, STAT1, STAT2, CCL2, CXCL1, SOCS1, SOCS3

Inflammatory and immune response

CCL3, CCR1, CD163, FCGR1A, IL1R2, IL1B, IL1RN, IL-8, NFAT5, TRA@, MAP2K3, MAP2K6, SMAD3, FCGR2A, FCGR2B, NFKBIA

Cellular proliferation and differentiation

CDKN1C, CDK1A, DUSP1, EP300, FOS, JUN, PRKACA, PRKACB

Protein folding

SLP1

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BMC Medicine

ISSN: 1741-7015

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