Table 1 Characteristics of included studies for the association between DM and TB outcomes
From: The impact of diabetes on tuberculosis treatment outcomes: A systematic review
| Â | Â | Â | Â | Â | Â | Outcomes | Â | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Study | Type of study | Country | Type of TB | Total n | Population with DM n | Sputum Culture Conversion 2-3 months | Failure And Death | Death | Adjusted Variables for Death Outcome | Relapse | DR Recurrence | DM Definition |
Alisjahbana [11] | Prospective cohort | Indonesia | Pulmonary TB | 634 | 94 | √ | √ | √ |  |  |  | 2 measurements of FBG > 126 mg/dL |
Ambrosetti [28] | Prospective cohort | Italy | Undifferentiated TB | 778 | 32 |  | √ | √ |  |  |  | Medical records |
Ambrosetti [29] | Prospective cohort | Italy | Undifferentiated TB | 838 | 50 |  | √ | √ |  |  |  | Medical records |
Ambrosetti [30] | Prospective cohort | Italy | Undifferentiated TB | 715 | 40 |  | √ | √ |  |  |  | Medical records |
Anunnatsiri [31] | Retrospective cohort | Thailand | Pulmonary TB | 226 | 117 |  | √ |  |  |  |  | Medical records |
Banu Rekha [32] | Retrospective analysis of 3 concurrent studies | India | Pulmonary TB | 190 | 92 | √ |  |  |  |  |  | Medical records, FBG |
Bashar [33] | Retrospective case-control | USA | Undifferentiated TB | 155 | 50 |  |  | √ |  |  |  | Medical records |
Blanco [34] | Retrospective cohort | Canary Islands, Spain | Pulmonary TB | 98 | 14 | √ |  |  |  |  |  | Medical records |
Centis [35] | Prospective cohort | Italy | Undifferentiated TB | 1,162 | 56 |  | √ | √ |  |  |  | Medical records |
Centis [36] | Prospective cohort | Italy | Undifferentiated TB | 906 | 40 |  | √ | √ |  |  |  | Medical records |
Chiang [37] | Retrospective cohort | Taiwan | Pulmonary TB | 1,127 | 241 |  | √ | √ |  |  |  | Medical records |
Dooley [12] | Retrospective cohort | USA | Undifferentiated TB | 297 | 42 | √ |  | √ | Age, HIV, weight, foreign birth |  |  | Medical records, non-FBG > 200 mg/dL, DM medications |
Fielder [38] | Retrospective cohort | USA | Pulmonary TB | 174 | 22 |  |  | √ | Age |  |  | Medical records |
Fisher-Hoch [39] | Retrospective cohort | Mexico & USA | Undifferentiated TB | 2,878 | 688 |  |  | √ |  |  | √ | Self report |
Guler [40] | Retrospective cohort | Turkey | Pulmonary TB | 306 | 44 | √ |  |  |  |  |  | Medical records |
Hara [41] | Retrospective cohort | Japan | Pulmonary TB | 624 | 112 | √ |  |  |  |  |  | Medical records |
Hasibi [42] | Retrospective cohort | Iran | Disseminated TB | 50 | 6 |  |  | √ |  |  |  | Medical records |
Ito [43] | Retrospective cohort | Japan | Undifferentiated TB | 109 | 16 |  |  |  |  |  | √ | Medical records |
Kitahara [44] | Retrospective cohort | Japan | Pulmonary TB | 520 | 71 | √ |  | √ |  |  |  | Medical records |
Kourbatova [45] | Retrospective case-control | Russia | Undifferentiated TB | 460 | 20 |  |  | √ |  |  |  | Medical records |
Maalej [46] | Retrospective case-control | Tunisia | Pulmonary TB | 142 | 60 |  |  | √ |  | √ |  | Medical records |
Mboussa [47] | Retrospective cohort | Republic of the Congo | Pulmonary TB | 132 | 32 |  | √ | √ |  | √ |  | 2 measurements of FBG ≥ 126 mg/dL |
Oursler [48] | Retrospective cohort | USA | Pulmonary TB | 139 | 18 |  |  | √ | Age, HIV, renal, COPD |  |  | Medical records |
Pina [49] | Retrospective cohort | Spain | Undifferentiated TB | 1,511 | 73 |  |  | √ |  |  |  | Medical records |
Ponce-De-Leon [3] | Prospective cohort | Mexico | Pulmonary TB | 581 | 172 |  | √ | √ |  |  |  | Medical records (FBG ≥ 126 mg/dL, non-FBG ≥ 200 mg/dL sensitivity analysis) |
Singla [50] | Retrospective cohort | Saudi Arabia | Pulmonary TB | 692 | 187 |  | √ | √ |  | √ |  | 2 measurements of FBG > 140 mg/dL |
Subhash [51] | Retrospective cohort | India | Undifferentiated TB | 361 | 72 |  |  |  |  |  | √ | FBG > 140 mg/dL, medical records and DM medication or diet |
Tatar [52] | Retrospective cohort | Turkey | Undifferentiated TB | 156 | 78 | √ |  | √ |  |  |  | Medical records |
Vasankari [53] | Retrospective cohort | Finland | Pulmonary TB | 629 | 92 |  |  | √ |  |  |  | Treatment with DM medications |
Wada [54] | Retrospective cohort | Japan | Pulmonary TB | 726 | 143 | √ |  |  |  | √ |  | Medical records |
Wang [55] | Retrospective cohort | Taiwan | Pulmonary TB | 453 | 75 |  |  |  |  |  | √ | Medical records |
Wang [56] | Retrospective cohort | Taiwan | Pulmonary TB | 217 | 74 |  | √ | √ | Age, sex |  |  | Medical records and DM medication or FBG > 126 mg/dL |
Zhang [57] | Retrospective Cohort | China | Pulmonary TB | 2,141 | 203 |  |  |  |  | √ |  | FBG ≥ 126 mg/dL |