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Table 4 Standardized dataset for the cost-effectiveness models in rotavirus vaccination: health-care use and costs

From: Comparative review of three cost-effectiveness models for rotavirus vaccines in national immunization programs; a generic approach applied to various regions in the world

  Afr Sear Amr Eur Notes
Average length of hospital stay 4 4 4 4 days
Cost per hospital day US$35 US$34 US$122 € 550  
Cost per outpatient visit (health center/GP) US$10.50 US$9 US$34.50 € 40 Community acquired only
Out-of-pocket costs (comm.-acq. only) US$0.50 US$2.5 US$5 € 15 diapers/travel/OTC
Total direct costs for nosocomial cases US$15 US$15 US$50 € 2,000  
Cost of productivity loss/day US$1 US$5 US$10 € 125  
Parents with work loss      
   Non-hospitalized 20% 20% 20% 20%  
   Hospitalized & nosocomial 75% 75% 75% 75%  
Days of work missed for parents      
   Mild 1 1 1 1  
   Moderate 1.5 1.5 1.5 1.5  
   Severe 2 2 2 2 also for nosocomial
Discount rates 3% 3% 3% 3% money & health
Administration costs per dose US$0.53 US$0.46 US$0.46 € 5  
  1. (Note: all mild cases were treated at home, all moderate additionally in an outpatient setting, such as outpatient hospital, general practitioner or health center and all severe cases additionally in hospital; all cases have out-of-pocket costs), plausible assumptions based on literature [2931] and expert opinions (MP & MJ))
  2. GP: general practitioner; comm.-acq: community acquired; OTC: over the counter