Diseases | Findings | Rodents | Nonhuman primates | Humans | References |
---|---|---|---|---|---|
Cancer | CR prevents a broad range of cancer incidences, including breast and gastrointestinal cancer. | Y | Y | Y/? | |
Diabetes | CR improves glucose homeostasis and prevents diabetes. | Y | Y | Y | |
Cardiovascular diseases | CR lowers blood pressure and favorably alters lipid profile, resulting in significantly reducing the risk of cardiovascular disease and related complications. | Y | Y | Y | |
Neurodegenerative diseases | CR reduces aging-associated neuronal loss and neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease. | Y | Y | Y/? | |
Immune deficiencies | CR delays the onset of T-lymphocyte-dependent autoimmune diseases. | Y | Y/? | Y/? | [21] |