|
Index
|
Estimate (95%CI)
|
|---|
|
Derivation indices (n = 2,724)
|
Internal validation by bootstrapping (n = 2,724)
|
Optimism-corrected indices (n = 2,724)
|
|---|
|
Sensitivity
|
0.940 (0.895, 0.984)
|
0.958 (0.890, 0.994)
|
0.929 (0.881, 0.954)
|
|
Specificity
|
0.799 (0.783, 0.815)
|
0.751 (0.614, 0.885)
|
0.799 (0.783, 0.815)
|
|
Likelihood ratio
|
|
Positive test result
|
4.670 (4.124, 5.309)
|
3.853 (2.570, 7.747)
|
4.624 (3.986, 4.887)
|
|
Negative test result
|
0.076 (0.019, 0.134)
|
0.056 (0.009, 0.125)
|
0.090 (0.056, 0.147)
|
|
Area under ROC curve
|
0.966 (0.951, 0.981)
|
0.961 (0.952, 0.966)
|
0.960 (0.944, 0.976)
|
- Obtained from internal validation by using a bootstrap analysis in which the cohort was resampled 1,000 times with replacement.Likelihood ratio for a positive test result refers to the likelihood of assignment to the high-risk group after step 2. Likelihood ratio for a negative test result refers to the likelihood of assignment to the low-risk group after steps 1 or 2. CI, confidence interval; ROC, receiver-operating characteristic.
