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Table 1 Baseline characteristics

From: Mesalazine in the initial management of severely acutely malnourished children with environmental enteric dysfunction: a pilot randomized controlled trial

Baseline characteristics Mesalazine arm Placebo arm
Number enrolled 22 22
Age (months) 19 (14 to 32) 19 (15 to 29)
Sex: Male 10 (45) 11 (50)
 Female 12 (55) 11 (50)
Household income category (USD/day)a $2 to $4 $2 to $4
Number of people living in the house 5 (4 to 7) 5 (4 to 5)
Access to improved drinking water sourceb 100% 100%
Access to improved toilet facility 50% 41%
MUAC (cm) 12.9 (11.2 to 14.4) 12.7 (11.2 to 13.8)
Height-for-age z-score -3.13 (-3.83 to -2.71) -3.73 (-4.60 to -2.81)
Nutritional edema 15 (68) 17 (77)
Current breastfeedingc 11 (50) 5 (23)
Symptoms: Fever 10 (45) 8 (36)
 Cough 9 (41) 6 (27)
 Diarrhea 5 (23) 5 (23)
Biochemistry: Creatinine (umol/L) 18 (17 to 23) 19 (17 to 22)
 AST (IU/L) 37 (27 to 52) 40 (32 to 49)
 ALT (IU/L) 24 (12 to 31) 17 (15 to 30)
 CRP (mg/L) 6.0 (1.3 to 10.8) 6.8 (1.6 to 42.2)
Hematology: Hemoglobin (g/dL) 10.3 (7.9 to11.2) 9.6 (8.2 to 10.6)
 WBC count (x 109/L) 12.0 (9.9 to 15.1) 11.8 (9.3 to 13.6)
 Platelet count (x 109/L) 555 (423 to 666) 536 (282 to 692)
 ESR (mm/hour) 32 (24 to 38) 33 (28 to 44)
  1. aMedian and IQR for both arms all fell within the $2 to $4 category. bMostly communal taps from which water must be purchased. Lack of resources was reported to limit access. c P = 0.06. Data are medians (inter-quartile range) or numbers (%). ALT, alanine transaminase; AST, aspartate aminotransferase; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; MUAC, mid-upper arm circumference; WBC, white blood cell.