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Table 1 Baseline characteristics

From: Mesalazine in the initial management of severely acutely malnourished children with environmental enteric dysfunction: a pilot randomized controlled trial

Baseline characteristics

Mesalazine arm

Placebo arm

Number enrolled

22

22

Age (months)

19 (14 to 32)

19 (15 to 29)

Sex: Male

10 (45)

11 (50)

 Female

12 (55)

11 (50)

Household income category (USD/day)a

$2 to $4

$2 to $4

Number of people living in the house

5 (4 to 7)

5 (4 to 5)

Access to improved drinking water sourceb

100%

100%

Access to improved toilet facility

50%

41%

MUAC (cm)

12.9 (11.2 to 14.4)

12.7 (11.2 to 13.8)

Height-for-age z-score

-3.13 (-3.83 to -2.71)

-3.73 (-4.60 to -2.81)

Nutritional edema

15 (68)

17 (77)

Current breastfeedingc

11 (50)

5 (23)

Symptoms: Fever

10 (45)

8 (36)

 Cough

9 (41)

6 (27)

 Diarrhea

5 (23)

5 (23)

Biochemistry: Creatinine (umol/L)

18 (17 to 23)

19 (17 to 22)

 AST (IU/L)

37 (27 to 52)

40 (32 to 49)

 ALT (IU/L)

24 (12 to 31)

17 (15 to 30)

 CRP (mg/L)

6.0 (1.3 to 10.8)

6.8 (1.6 to 42.2)

Hematology: Hemoglobin (g/dL)

10.3 (7.9 to11.2)

9.6 (8.2 to 10.6)

 WBC count (x 109/L)

12.0 (9.9 to 15.1)

11.8 (9.3 to 13.6)

 Platelet count (x 109/L)

555 (423 to 666)

536 (282 to 692)

 ESR (mm/hour)

32 (24 to 38)

33 (28 to 44)

  1. aMedian and IQR for both arms all fell within the $2 to $4 category. bMostly communal taps from which water must be purchased. Lack of resources was reported to limit access. c P = 0.06. Data are medians (inter-quartile range) or numbers (%). ALT, alanine transaminase; AST, aspartate aminotransferase; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; MUAC, mid-upper arm circumference; WBC, white blood cell.