From: Environmental stress and epigenetic transgenerational inheritance
Exposure | Pathology | Reference |
---|---|---|
Toxicants | ||
Vinclozolin | Testis, prostate, kidney disease, tumors, immune | |
 | Gender-specific changes in anxiety-like behavior | Skinner et al., 2008 [13] |
 | Immune and reproductive | Nilsson et al., 2008 [14] |
Methoxychlor | Testis, kidney, ovary, obesity | |
Permethrin/DEET | Prostate, kidney disease | Manikkam et al. 2012 [16] |
Dioxin | Prostate, kidney, fertility, pregnancy | |
BPA/phthalates | Prostate, kidney, obesity | Manikkam et al. 2013 [19] |
Hydrocarbon mixture (jet fuel) | Prostate, kidney, obesity, immune and reproduction | Tracey et al. 2013 [20] |
Vinclozolin, permethrin/DEET, plastics, dioxin, jet fuel | Polycystic ovaries, reduced primordial follicle pool | Nilsson et al. 2012 [21] |
DDT | Obesity, kidney, testis | Skinner et al. 2013 [5] |
Phthalate | Testis and spermatogonial stem cell | Doyle et al. 2013 [22] |
Tributyltin | Obesity and adipose cell | Chamorro-Garcia et al. 2013 [23] |
BPA | Social behavior, implantation, litter size, sperm | |
Others | ||
Caloric restriction | Cardiovascular mortality | Bygren et al. 2014 [26] |
High fat diet | Growth and insulin sensitivity | Dunn and Bale 2011 [6] |
Folate | Congenital malformations | Padmanabhan et al. 2013 [27] |
Drought | DNA methylation changes | Zheng et al. 2013 [7] |
Heat/salt | Flowering and salt tolerance | Suter and Widmer 2013 [28] |
Prediabetes | Glucose tolerance and insulin sensitivity | Wei et al. 2014 [29] |
Smoking | Abnormal pulmonary function | Rehan et al. 2013 [30] |
Alcohol | Endocrine and neuronal function | Govorko et al. 2012 [31] |
Heat stress | Increased Hsp70 production and tolerance to heat stress | Norouzitallab et al. 2014 [8] |