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Table 3 Sensitivity and specificity of exclusion/inclusion cutoff points of LFS, FLI, and HSI in the cross-sectional NAFLD prediction cohort and literature

From: Non-invasive score identifies ultrasonography-diagnosed non-alcoholic fatty liver disease and predicts mortality in the USA

NAFLD definition Non-invasive NAFLD score Cutoff point SP, % 95% CI, % SN, % 95% CI, % Reported SP, % Reported SN, % Ref
No to mild versus intermediate to severe steatosis) LFS Inclusion  1.257 96.43 95.82 to 96.98 26.34 23.71 to 29.09 95 51 [7]
Exclusion ≤ −1.413 67.94 66.49 to 69.36 73.95 71.20 to 76.56 52 95
FLI Inclusion  60 73.60 72.22 to 74.94 67.48 64.58 to 70.29 86 61 [6]
Exclusion <30 48.77 47.24 to 50.31 84.44 82.13 to 86.57 64 87
HSI Inclusion  36 69.35 67.91 to 70.75 66.26 63.33 to 69.10 92 46 [9]
Exclusion <30 29.75 28.36 to 31.18 91.38 89.53 to 92.99 40 92.50
  1. AUC, area under the curve; FLI, fatty liver index; HSI, hepatic steatosis index; LAP, lipid accumulation product; LFS, liver fat score; NAFLD, non-alcoholic fatty liver disease; SN, sensitivity; SP, specificity.