Multivariable-adjusted hazard ratios (95% confidence intervals) of colorectal cancer according to increasing number of healthy lifestyle factors. Healthy lifestyle index (range 0 to 5 points) is calculated by summing the binary lifestyle factor variables (0, 1) including overweight and obesity, physical activity, smoking, alcohol consumption and diet quality. Participants received 1 point if they had any of the following behaviours: healthy weight, physically active, non-smokers or former smokers, limited alcohol consumption or healthy diet quality. The hazard ratios are calculated after stratification by EPIC study centre and multivariable adjustment for age at study recruitment, sex and educational status (none, primary school, technical/professional school/not specified). P-value for the linear trend was calculated using the Wald test treating the index as a continuous variable. EPIC. European Prospective Investigation into Cancer and Nutrition.