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Table 2 Two-year changes in HRQL scores

From: Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study

 

Unadjusted change from baseline (mean (SD))

Adjusted difference in differences (points (95% CI))

Instrument

Wait-listed

Medical management

Surgical treatment

P-valuea

Medical (wait-list subtracted)

Surgery (wait-list subtracted)

Surgery (medical subtracted)

(n = 150)

(n = 200)

(n = 150)

SF-12 PCS

1.0 (6.7)

5.0 (7.1)

6.2 (9.2)

<0.001

4.5 (2.9, 6.0)

6.8 (5.1, 8.5)

2.3 (0.7, 3.9)

SF-12 MCS

0.7 (7.7)

4.0 (9.6)

1.0 (10.6)

0.011

4.2 (2.3, 6.0)

3.2 (1.1, 5.3)

-1.0 (-2.9, 0.9)

EQ-Index

0.01 (0.17)

0.07 (0.16)

0.05 (0.18)

0.002

0.07 (0.04, 0.10)

0.08 (0.04, 0.11)

0.00 (-0.03, 0.04)

EQ-VAS

5.7 (19.1)

11.1 (20.8)

12.5 (21.7)

0.009

6.9 (3.4, 10.4)

13.6 (9.7, 17.4)

6.7 (3.1, 10.2)

IWQOL-Lite Total Score

3.2 (13.8)

13.8 (15.5)

26.9 (21.4)

<0.001

11.4 (8.1, 14.7)

25.7 (22.1, 29.3)

14.3 (11.0, 17.6)

  1. aANOVA. Comparisons adjusted for age, sex, baseline BMI and baseline HRQL score. EQ-Index, Euroqol-5D questionnaire index score; EQ-VAS, Euroqol-5D questionnaire visual analog scale score; HRQL, health-related quality of life; IWQOL-Lite, Impact of Weight on Quality of Life - Lite questionnaire; MCS, mental component summary score; PCS, physical component summary score; SF-12, Short Form 12 questionnaire.