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Table 2 Two-year changes in HRQL scores

From: Weight loss required by the severely obese to achieve clinically important differences in health-related quality of life: two-year prospective cohort study

  Unadjusted change from baseline (mean (SD)) Adjusted difference in differences (points (95% CI))
Instrument Wait-listed Medical management Surgical treatment P-valuea Medical (wait-list subtracted) Surgery (wait-list subtracted) Surgery (medical subtracted)
(n = 150) (n = 200) (n = 150)
SF-12 PCS 1.0 (6.7) 5.0 (7.1) 6.2 (9.2) <0.001 4.5 (2.9, 6.0) 6.8 (5.1, 8.5) 2.3 (0.7, 3.9)
SF-12 MCS 0.7 (7.7) 4.0 (9.6) 1.0 (10.6) 0.011 4.2 (2.3, 6.0) 3.2 (1.1, 5.3) -1.0 (-2.9, 0.9)
EQ-Index 0.01 (0.17) 0.07 (0.16) 0.05 (0.18) 0.002 0.07 (0.04, 0.10) 0.08 (0.04, 0.11) 0.00 (-0.03, 0.04)
EQ-VAS 5.7 (19.1) 11.1 (20.8) 12.5 (21.7) 0.009 6.9 (3.4, 10.4) 13.6 (9.7, 17.4) 6.7 (3.1, 10.2)
IWQOL-Lite Total Score 3.2 (13.8) 13.8 (15.5) 26.9 (21.4) <0.001 11.4 (8.1, 14.7) 25.7 (22.1, 29.3) 14.3 (11.0, 17.6)
  1. aANOVA. Comparisons adjusted for age, sex, baseline BMI and baseline HRQL score. EQ-Index, Euroqol-5D questionnaire index score; EQ-VAS, Euroqol-5D questionnaire visual analog scale score; HRQL, health-related quality of life; IWQOL-Lite, Impact of Weight on Quality of Life - Lite questionnaire; MCS, mental component summary score; PCS, physical component summary score; SF-12, Short Form 12 questionnaire.