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Table 2 Evidence levels[8]

From: Pain care for patients with epidermolysis bullosa: best care practice guidelines

Quality level Definition
1aa or 1ba Systematic review, meta-analysis, or meta-synthesis of multiple studies
2a or 2b Best study design for domain
3a or 3b Fair study design for domain
4a or 4b Weak study design for domain
5a or 5b General review, expert opinion, case report, consensus report, or guideline
5 Local Consensus
  1. aa = good quality study; b = lesser quality study.