MSC dynamics in patients’ bone marrow (BM) and peripheral blood (PB) over time post injury. A) MSC changes in aspirated BM at different time-points post-injury (split into Subgroups: Early (Days 1 to 3 post injury), Intermediate (days 4 to 10 post injury), Late (more than 11 days post injury) and Return to baseline (more than 1 year post injury). The solid line represents polytrauma patients and the broken line represents isolated trauma patients; thick bars represent median values. B) Representative Day 0 CFU-F dishes from patients from the corresponding subgroups, demonstrating the abundance of CFU-Fs in the BM and their absence in PB. CFU-F, colony-forming unit – fibroblast; MSC, mesenchymal stem cell.