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Table 2 Previous studies of intratympanic dexamethasone therapy as a salvage treatment

From: A randomized controlled clinical trial of topical insulin-like growth factor-1 therapy for sudden deafness refractory to systemic corticosteroid treatment

  No. of patients PTA recovery Dexamethasone concentration Doses Proportion of recovery (%)
Ho et al. [9] 15 28 dB 4 mg/mL 3 doses, once a week 53%
Choung et al. [10] 34 9 dB 5 mg/mL 4 doses, twice a week 39%
Roebuck et al. [11] 31 12 dB 24 mg/mL Single 29%
Haynes et al. [12] 40 5 dB 24 mg/mL Single 27.5%
Plontke et al. [13] 11 14 dB 4 mg/mL Pump for 14 days 45%
Kakehata et al. [14] 24 17 dB 4 mg/mL 15 doses 58%
Lee et al. [15] 34 NA 4 mg/mL 6 doses for 14 days 21%
Mean (95% CI) 27 (21-33)     39% (30%-48%)
  1. PTA, Pure-tone audiometry; NA, Not available; CI, Confidential interval.