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Table 1 Characteristics of included guidelines and consensus statements

From: Diagnosis and treatment of hyponatremia: a systematic review of clinical practice guidelines and consensus statements

Developer

Year

Country

Funding source

Target population

Target users

Guideline writers

Guideline review

Guideline update

Methods support

Evidence base

Europe

          

NIV

2012

Netherlands

Government funding

Adults with hyponatremia

Clinicians, Internists

Multidisciplinary internists, epidemiologist

Dutch Association of Internists (NIV), expert peer review

In case of breakthrough changes in diagnosis or treatment

PROVA – company specialized in Evidence Based Guideline Development

Systematic literature review

NHS

2011

UK

NS

Adults with hyponatremia in primary care

Primary care professionals within NHS

NS

NS

Planned in 2015

NS

Systematic literature review

GAIN*

2010

Northern Ireland

Government funding

Adults with hyponatremia

NS

Multidisciplinary anesthetists, clinical chemist, nephrologist

NS

3 years

NS

NS

AEEH*

2003-2004

Spain

NS

Patients with cirrhosis

NS

Gastroenterologists

NS

NS

NS

NS

EHN*

2013

Spain

NS

Hospitalized patients with SIADH

NS

Multidisciplinary endocrinologists, nephrologists, internists, hospital pharmacist

NS

NS

NS

Consensus statements

ERBP/ESE/ESICM

2014

Europe

Unrestricted grant from participating societies

Adults with hyponatremia

Health care professionals dealing with hyponatremia

Multidisciplinary nephrologists, endocrinologists, general internists, critical care physicians

External review by KHA-CARI, ESA, and members ERA-EDTA

5 years or earlier in case of new evidence requiring changes

ERBP methods support team

Systematic literature review

North America

          

UF

2008-2009

USA

NS

Neurosurgery patients with hyponatremia

NS

Multidisciplinary neurosurgeons, nurse practitioners, nephrologists, critical care physician, endocrinologist, pharmacist, nurses

NS

NS

NS

Systematic literature review

HEP

2013

USA

Funding Unrestricted educational grant from pharmaceutical company

Patients with hyponatremia

NS

Endocrinologist, nephrologists

NS

NS

NS

Systematic literature review

Australia

          

RCHM*

2012

Australia

NS

Children

NS

NS

External review within the hospital where appropriate’

12 to 24 months

NS

NS

International

          

EAH- ICD*

2007

USA, Canada, UK, Switzer-land, Canada, South Africa, New Zealand, Australia

No commercial sponsorship’

People with exercise-associated hyponatremia

Medical personnel, athletes, greater public

Multidisciplinary endocrinologist, epidemiologist, nephrologists, emergency medicine physician, general practitioner, internist, sports physicians, exercise physiologists

NS

NS

NS

Systematic literature review

  1. NIV, Nederlandse Internisten Vereniging [16]; NHS, National Health Service [17]; GAIN, Guidelines and Audit Implementation Network [22]; AEEH, La Asociación Española para el Estudio del Hígado [23]; EHN, European Hyponatremia Network [25]; ERBP, European Renal Best Practice; ESE, European Society of Endocrinology; ESICM, European Society of Intensive Care Medicine [20]; UF, University of Florida [18]; HEP, Hyponatremia Expert Panel [19]; RCH Melbourne, the Royal Children’s Hospital Melbourne [21]; EAH-ICD, International Exercise-Associated Hyponatremia Consensus Development Conference [24]; [Na], Serum sodium concentration; NS, Not stated; KHA-CARI, Kidney Health Australia, Caring for Australasians with Renal Impairment; ESA, Endocrine Society of Australia; ERA-EDTA, European Renal Association; European Dialysis and Transplant Association; *Classified as consensus statement.